Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132487 | 0.88 | — | — | |
| SCHEMBL4181102 | 0.84 | TSHR (0.42) | ALDH1A1POLBTSHRLMNAHTT | |
| SCHEMBL12047395 | 0.83 | ALDH1A1 (0.31) | ALDH1A1LMNAHTT | |
| SCHEMBL30917913 | 0.79 | TDP1 (0.38) | ALDH1A1POLBTSHRLMNAHTT | |
| SCHEMBL13415764 | 0.78 | MAPT (0.32) | ALDH1A1POLBTSHRLMNAHTT | |
| SCHEMBL19343371 | 0.75 | DGKA (0.44) | ALDH1A1POLBTSHRLMNA | |
| SCHEMBL11660336 | 0.75 | DGKA (0.44) | ALDH1A1POLBTSHRLMNA | |
| SCHEMBL17081052 | 0.75 | DGKA (0.44) | ALDH1A1POLBTSHRLMNA | |
| SCHEMBL18746603 | 0.74 | L3MBTL1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL13324469 | 0.73 | THRB (0.41) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120067249-A1 | MOISTURE CURABLE POLYDISULFIDES | HENKEL AG & CO. KGAA (DE) | 2012-03-22 | — | — | US | disclosed |
| US-8063237-B2 | Sulfur modified silanes for the elaboration of high refractive index materials | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2011-11-22 | — | — | US | disclosed |
| US-20110077341-A1 | SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS | ESSILOR INTERNATIONAL (FR) | 2011-03-31 | — | — | US | disclosed |
| US-7867577-B2 | hydrolyzed, concentrated, and heated polysulfides, alkenyl silanes such as vinyltrimethoxysilane; for formation of lenses | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2011-01-11 | — | — | US | disclosed |
| US-20090287015-A1 | SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS | ESSILOR INTERNATIONAL (FR) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077341-A1 | SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS | TST, LAGE3, PSME1 | ALDH1A1 814/4885POLB 1713/4885TSHR 3396/4885 |
| US-20120067249-A1 | MOISTURE CURABLE POLYDISULFIDES | ASH2L, STOM, ESD | ALDH1A1 2515/4885POLB 786/4885TSHR 4881/4885 |
| US-20090287015-A1 | SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS | LAGE3, TST, PSME1 | ALDH1A1 713/4885POLB 1517/4885TSHR 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.