Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182256 | 1.00 | SLC7A5 (0.45) | SLC7A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL16574787 | 0.87 | SLC7A5 (0.52) | SLC7A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL27762534 | 0.85 | ALDH1A1 (0.50) | SLC7A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL20543766 | 0.85 | ALDH1A1 (0.50) | SLC7A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL21117864 | 0.85 | ALDH1A1 (0.50) | SLC7A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL22479129 | 0.84 | SLC15A1 (0.47) | SLC7A5IDO1GRIA2ALPIPKM | |
| SCHEMBL11856496 | 0.84 | GRIA2 (0.55) | SLC7A5NOS3NOS1NOS2GRIA2 | |
| SCHEMBL2038370 | 0.84 | GRIA2 (0.55) | SLC7A5NOS3NOS1NOS2GRIA2 | |
| SCHEMBL21117781 | 0.82 | PNMT (0.57) | SLC7A5NOS3NOS1NOS2MAPK1 | |
| SCHEMBL7339183 | 0.82 | SLC1A1 (0.54) | SLC7A5NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1930315-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & COMPANY, LTD. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | AADAT, BCAT2, BCAT1 | SLC7A5 9/4885NOS3 805/4885NOS1 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.