Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178311 | 0.91 | PDE10A (0.35) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4183205 | 0.88 | KDM4E (0.33) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL4185269 | 0.86 | KDM4E (0.34) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4178062 | 0.86 | PDE4A (0.34) | KDM4EALDH1A1POLBGAATSHR | |
| SCHEMBL4191730 | 0.86 | SLC10A2 (0.33) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4187144 | 0.81 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL4189834 | 0.78 | MAPK1 (0.37) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12070947 | 0.75 | KDM4E (0.41) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4177976 | 0.75 | KMT2A (0.31) | KDM4EKMT2AGAAPDE4DPDE10A | |
| SCHEMBL996497 | 0.73 | CCR1 (0.42) | MAPTMEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009014730-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |