Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191730 | 0.90 | SLC10A2 (0.33) | MEN1KMT2APOLBGAARAD52 | |
| SCHEMBL4182845 | 0.88 | MAPT (0.34) | KDM4EHPGDHSD17B10PDE10AMEN1 | |
| SCHEMBL4177976 | 0.87 | KMT2A (0.31) | KDM4EPDE10AKMT2AGAATRPM8 | |
| SCHEMBL4178311 | 0.86 | PDE10A (0.35) | KDM4EHPGDHSD17B10PDE10AMEN1 | |
| SCHEMBL4178062 | 0.83 | PDE4A (0.34) | KDM4EHPGDPOLBGAA | |
| SCHEMBL4187144 | 0.78 | ALDH1A1 (0.38) | KDM4EHSD17B10KMT2ARAD52MAPT | |
| SCHEMBL4177972 | 0.77 | SLC10A2 (0.33) | KDM4EKMT2AGAARAD52 | |
| SCHEMBL4185269 | 0.75 | KDM4E (0.34) | KDM4EUSP2HPGDHSD17B10MEN1 | |
| SCHEMBL4189834 | 0.73 | MAPK1 (0.37) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL13226974 | 0.73 | RAC1 (0.32) | KDM4EMEN1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009014730-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |