Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177972 | 0.90 | SLC10A2 (0.33) | KMT2ARAD52KDM4EGAAHTT | |
| SCHEMBL4185269 | 0.88 | KDM4E (0.34) | KMT2ARAD52KDM4EHTTPDPK1 | |
| SCHEMBL4183205 | 0.87 | KDM4E (0.33) | KMT2ATRPM8RAD52PDE10AKDM4E | |
| SCHEMBL4189834 | 0.86 | MAPK1 (0.37) | KMT2ARAD52KDM4EHTTPDPK1 | |
| SCHEMBL4182671 | 0.83 | KDR (0.35) | KMT2AKDM4EGAAHTTPDE4D | |
| SCHEMBL4177982 | 0.78 | ACHE (0.40) | KDM4EPDPK1 | |
| SCHEMBL4191730 | 0.77 | SLC10A2 (0.33) | KMT2ARAD52GAAHTTPDE4D | |
| SCHEMBL4182845 | 0.75 | MAPT (0.34) | KMT2ARAD52PDE10AKDM4EGAA | |
| SCHEMBL4178311 | 0.73 | PDE10A (0.35) | KMT2ARAD52PDE10AKDM4EGAA | |
| SCHEMBL4177973 | 0.72 | FGFR1 (0.41) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009014730-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |