Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183379 | 0.92 | STAT6 (0.38) | JAK3GBA1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4183372 | 0.87 | STAT6 (0.38) | JAK3GBA1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4184004 | 0.85 | GBA1 (0.44) | JAK3GBA1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL1630574 | 0.81 | GBA1 (0.43) | GBA1NR3C2ADRB1ADRB3ADRB2 | |
| SCHEMBL4185958 | 0.80 | STAT6 (0.39) | JAK3TSHRSMN1; SMN2STAT6NR3C2 | |
| SCHEMBL1632043 | 0.80 | ALDH1A1 (0.40) | PTAFRJAK3GBA1CYP1A2CYP3A4 | |
| SCHEMBL4186002 | 0.80 | GBA1 (0.46) | GBA1NR3C2ADRB1ADRB3ADRB2 | |
| SCHEMBL13743392 | 0.79 | LMNA (0.44) | PTAFRJAK3GBA1CYP1A2CYP3A4 | |
| SCHEMBL1629879 | 0.77 | GBA1 (0.39) | GBA1ALDH1A1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL1632673 | 0.77 | GBA1 (0.47) | GBA1NR3C2ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | PTAFR 1043/4885JAK3 2944/4885GBA1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.