Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175138 | 0.87 | — | — | |
| SCHEMBL7837979 | 0.71 | ALDH1A1 (0.59) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL4512497 | 0.71 | ALDH1A1 (0.57) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL4506995 | 0.71 | ALDH1A1 (0.59) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8910367 | 0.71 | L3MBTL1 (0.63) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8910362 | 0.71 | L3MBTL1 (0.63) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8909943 | 0.70 | ALDH1A1 (0.66) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8909936 | 0.70 | ALDH1A1 (0.66) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8196728 | 0.70 | SLC6A1 (0.63) | HTR7HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL8196471 | 0.70 | SLC6A1 (0.63) | HTR7HTR1ADRD2HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137637-A1 | Tetrazolyl-Methylene Amino Acid Derivatives | PFIZER INC. (US) | 2009-05-28 | — | — | US | disclosed |
| EP-1828162-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006061706-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137637-A1 | Tetrazolyl-Methylene Amino Acid Derivatives | MMP13, MMP11, MMP3 | HTR7 2242/4885HTR1A 869/4885DRD2 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.