Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532006 | 0.83 | TAS1R3 (0.51) | HPGDLMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL18434389 | 0.80 | HPGD (0.77) | HPGDKDM4ELMNAGAAKMT2A | |
| SCHEMBL6361467 | 0.80 | KMT2A (0.61) | HPGDKDM4EKMT2ASMN1; SMN2TSHR | |
| SCHEMBL531992 | 0.80 | SMN1; SMN2 (0.57) | KMT2AMLYCDSMN1; SMN2ALPLNPSR1 | |
| SCHEMBL10324045 | 0.79 | KDM4E (1.00) | HPGDKDM4ELMNAGAAKMT2A | |
| SCHEMBL22231390 | 0.79 | MAOA (0.50) | HPGDKMT2ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL13859182 | 0.79 | SMN1; SMN2 (0.53) | HPGDKDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL19835598 | 0.78 | HPGD (0.73) | HPGDKDM4EKMT2ASMN1; SMN2TSHR | |
| SCHEMBL17847355 | 0.78 | KMT2A (0.78) | HPGDKDM4ELMNAGAAKMT2A | |
| SCHEMBL17865783 | 0.78 | MLYCD (0.73) | HPGDKDM4ELMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192163-A1 | Novel Compounds | PAH, PC, DDC | HPGD 746/4885KDM4E 2302/4885LMNA 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.