Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963317 | 0.85 | TAS2R14 (0.48) | SMN1; SMN2NFE2L2TAS2R14ALDH1A1SIRT2 | |
| SCHEMBL4818070 | 0.85 | PKM (0.50) | SMN1; SMN2MAPTGAANFE2L2ALDH1A1 | |
| SCHEMBL4818974 | 0.81 | EGFR (0.56) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14303718 | 0.78 | DYRK1A (0.50) | MAPTGAANFE2L2ALDH1A1SIRT2 | |
| SCHEMBL6208314 | 0.77 | HSD11B1 (0.53) | MEN1KMT2AMAPTGAANFE2L2 | |
| SCHEMBL4250924 | 0.77 | HSD11B1 (0.53) | GAANFE2L2TAS2R14PGRHSD11B1 | |
| SCHEMBL4209577 | 0.77 | ALDH1A1 (0.59) | SMN1; SMN2MAPTTAS2R14ALDH1A1PGR | |
| SCHEMBL3427100 | 0.77 | NFE2L2 (0.48) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL9820015 | 0.76 | MAPT (0.61) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4188124 | 0.75 | HSD11B1 (0.48) | SMN1; SMN2NFE2L2TAS2R14PGRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2008157216-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | HTR6, HTR2B, HTR3B | MEN1 2376/4885KMT2A 648/4885SMN1; SMN2 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.