Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | MC3R | P41968 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943969 | 0.86 | DRD2 (0.46) | HTR2AHTR7DRD2KCNH2GABRA1 | |
| SCHEMBL4200459 | 0.76 | RAB9A (0.43) | HTR2AHTR7DRD2GABRA1GABRG2 | |
| SCHEMBL3943143 | 0.73 | RAB9A (0.51) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3950113 | 0.73 | ALDH1A1 (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4199731 | 0.72 | ALDH1A1 (0.42) | HTR2AHTR7DRD2KCNH2KMT2A | |
| SCHEMBL3943966 | 0.72 | RAB9A (0.43) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3942488 | 0.71 | RAB9A (0.49) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL4347563 | 0.70 | MAPT (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3129331 | 0.69 | MEN1 (0.42) | HTR2AHTR7DRD2KCNH2GABRA1 | |
| SCHEMBL3265904 | 0.69 | RAB9A (0.58) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |