Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202719 | 0.85 | ALOX5 (0.53) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL1626763 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL4910068 | 0.83 | PIK3CA (0.47) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL85537 | 0.82 | LIPE (0.52) | MEN1KMT2ARAB9AMTORCMA1 | |
| SCHEMBL7431121 | 0.82 | HTT (0.57) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL2365836 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4690718 | 0.80 | MEN1 (0.71) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4196712 | 0.80 | PKM (0.67) | ALDH1A1RAB9AHTTHPGDHSP90AA1 | |
| SCHEMBL16703298 | 0.79 | CMA1 (0.54) | ALDH1A1KMT2AMTORCMA1F10 | |
| SCHEMBL7906874 | 0.79 | F10 (0.53) | ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103360380-B | A kind of synthetic method of razaxaban and the intermediate of razaxaban and preparation thereof | ZHEJIANG TIANYU PHARMACEUTICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103360380-A | Synthesis method of rivaroxaban, and rivaroxaban intermediate and preparation thereof | ZHEJIANG TIANYU PHARMACEUTICAL CO LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-101875654-A | The preparation method of 3-acyl amino cumarone-2-carboxylic acid derivative | TANABE SEIYAKU CO | 2010-11-03 | — | — | CN | disclosed |
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | SEKI MASAHIKO | 2009-01-22 | — | — | US | disclosed |
| US-7439368-B2 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| EP-1603572-A4 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-25 | — | — | EP | disclosed |
| US-20070135428-A1 | LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-14 | — | — | US | disclosed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| CN-1842528-A | Process for preparing 3-acylaminobenzofuran-2-carboxylic acid derivatives | TANABE SEIYAKU CO (JP) | 2006-10-04 | — | — | CN | disclosed |
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-08-03 | — | — | US | disclosed |
| EP-1640373-A1 | PROCESS FOR PRODUCING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1603572-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040204454-A1 | Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135428-A1 | LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | F12, F2, PEPD | ALDH1A1 3204/4885SMN1; SMN2 2952/4885POLB 2080/4885 |
| US-20040204454-A1 | Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors | PEPD, TFPI, F2 | ALDH1A1 3153/4885SMN1; SMN2 3010/4885POLB 2045/4885 |
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | F12, F3, F11 | ALDH1A1 661/4885SMN1; SMN2 4062/4885POLB 2550/4885 |
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | F12, F3, F11 | ALDH1A1 690/4885SMN1; SMN2 3833/4885POLB 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.