Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498136 | 1.00 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL427792 | 1.00 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL28499295 | 1.00 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL425128 | 0.98 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL10027723 | 0.96 | LMNA (0.61) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL14666490 | 0.96 | LMNA (0.61) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL17965504 | 0.96 | LMNA (0.61) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL14666520 | 0.92 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL421573 | 0.92 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL14666437 | 0.92 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250241-B1 | SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES | CHEVRON USA INC (US) | 2016-12-21 | — | — | EP | claimed |
| EP-2121567-B1 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON USA INC (US) | 2016-08-10 | — | — | EP | claimed |
| EP-2992072-A1 | DIESTER-BASED BASE OIL BLENDS WITH IMPROVED COLD FLOW PROPERTIES AND LOW NOACK | Chevron U.S.A. Inc. (US) | 2016-03-09 | — | — | EP | claimed |
| US-9109238-B2 | Synthesis of diester-based lubricants from enzymatically-directed epoxides | CHEVRON U.S.A. INC. (US) | 2015-08-18 | — | — | US | claimed |
| US-20150140623-A1 | Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides | NOVOZYMES A/S (DK) | 2015-05-21 | — | — | US | claimed |
| US-20140342960-A1 | BASE OIL BLEND UPGRADING PROCESS WITH A DIESTER BASE OIL TO YIELD IMPROVED COLD FLOW PROPERTIES AND LOW NOACK | CHEVRON U.S.A. INC. (US) | 2014-11-20 | — | — | US | claimed |
| US-20140342959-A1 | DIESTER-BASED BASE OIL BLENDS WITH IMPROVED COLD FLOW PROPERTIES AND LOW NOACK | CHEVRON U.S.A. INC. (US) | 2014-11-20 | — | — | US | claimed |
| US-20140342961-A1 | DIESTER-BASED ENGINE OIL FORMULATIONS WITH IMPROVED LOW NOACK AND COLD FLOW PROPERTIES | CHEVRON U.S.A. INC. (US) | 2014-11-20 | — | — | US | claimed |
| WO-2014179726-A1 | DIESTER-BASED ENGINE OIL FORMULATIONS WITH IMPROVED LOW NOACK AND COLD FLOW PROPERTIES | CHEVRON U.S.A. INC. (US) | 2014-11-06 | — | — | WO | claimed |
| WO-2014179723-A1 | DIESTER-BASED BASE OIL BLENDS WITH IMPROVED COLD FLOW PROPERTIES AND LOW NOACK | CHEVRON U.S.A. INC. (US) | 2014-11-06 | — | — | WO | claimed |
| US-7871967-B2 | Diester-based lubricants and methods of making same | CHEVRON U.S.A. INC. (US) | 2011-01-18 | — | — | US | claimed |
| US-7867959-B2 | Synthesis of diester-based biolubricants from epoxides | CHEVRON U.S.A. INC. (US) | 2011-01-11 | — | — | US | claimed |
| EP-2250241-A1 | SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES | Chevron U.S.A. Inc. (US) | 2010-11-17 | — | — | EP | claimed |
| WO-2010056832-A2 | SYNTHESIS OF DIESTER-BASED LUBRICANTS FROM ENZYMATICALLY-DIRECTED EPOXIDES | CHEVRON U.S.A. INC. (US) | 2010-05-20 | — | — | WO | claimed |
| US-20100120642-A1 | SYNTHESIS OF DIESTER-BASED LUBRICANTS FROM ENZYMATICALLY-DIRECTED EPOXIDES | CHEVRON U.S.A. INC. (US) | 2010-05-13 | — | — | US | claimed |
| EP-2121567-A2 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | Chevron U.S.A., Inc. (US) | 2009-11-25 | — | — | EP | claimed |
| US-20090198075-A1 | SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES | CHEVRON U.S.A. INC. (US) | 2009-08-06 | — | — | US | claimed |
| WO-2009097041-A1 | SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES | CHEVRON U.S.A. INC. (US) | 2009-08-06 | — | — | WO | claimed |
| WO-2008100822-A2 | DIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON U.S.A. INC. (US) | 2008-08-21 | — | — | WO | claimed |
| US-20080194444-A1 | Diester-Based Lubricants and Methods of Making Same | CHEVRON U.S.A. INC. (US) | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140623-A1 | Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides | DGAT2, ADH1A, ELOVL1 | LMNA 4747/4885MAPT 3281/4885MAPK1 3002/4885 |
| US-20090198075-A1 | SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES | ELOVL5, ELOVL1, ELOVL3 | LMNA 4543/4885MAPT 1348/4885MAPK1 3988/4885 |
| US-20080194444-A1 | Diester-Based Lubricants and Methods of Making Same | DGAT2, DGAT1, FADS1 | LMNA 4799/4885MAPT 2489/4885MAPK1 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.