Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | MMP7 | P09237 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | CTSE | P14091 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22499906 | 0.88 | ALDH1A1 (0.63) | ALDH1A1STSGPR119HTTMAPT | |
| SCHEMBL17892067 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MMP13GPR119HTTMAPT | |
| SCHEMBL25326881 | 0.87 | MMP13 (0.53) | ALDH1A1MMP13GPR119HTTMAPT | |
| SCHEMBL17892126 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MMP13GPR119HTTMAPT | |
| SCHEMBL4248552 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL5049579 | 0.78 | SLC6A3 (0.53) | ALDH1A1MMP1MMP3MMP7MMP13 | |
| SCHEMBL12533230 | 0.77 | GPR119 (0.67) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL7871974 | 0.77 | ALDH1A1 (0.67) | ALDH1A1STSGPR119BACE1CTSD | |
| Water SCHEMBL28845747 | 0.77 | SLC6A3 (0.52) | ALDH1A1NPC1MAPK1RAB9AEPHX2 | |
| SCHEMBL22499826 | 0.77 | NPC1 (0.55) | ALDH1A1GPR119BACE1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186921-A1 | AZACYCLIC COMPOUNDS | ACADIA PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2007124136-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186921-A1 | AZACYCLIC COMPOUNDS | HTR6, HTR5A, HNMT | ALDH1A1 1235/4885MMP1 1733/4885MMP3 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.