Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 2/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636671 | 0.87 | MEN1 (0.57) | ALDH1A1EPHX2SIGMAR1MEN1KMT2A | |
| SCHEMBL3642671 | 0.87 | MEN1 (0.57) | ALDH1A1EPHX2SIGMAR1MEN1KMT2A | |
| SCHEMBL654137 | 0.87 | LMNA (0.60) | ALDH1A1SIGMAR1MEN1KMT2ASTS | |
| Bromide SCHEMBL2636355 | 0.86 | MEN1 (0.56) | ALDH1A1EPHX2SIGMAR1MEN1KMT2A | |
| SCHEMBL24011150 | 0.85 | SMN1; SMN2 (0.64) | ALDH1A1EPHX2MEN1KMT2ASTS | |
| SCHEMBL23387204 | 0.85 | ALDH1A1 (0.68) | ALDH1A1EPHX2MEN1KMT2AGPR119 | |
| SCHEMBL7381166 | 0.85 | ALDH1A1 (0.69) | ALDH1A1EPHX2MEN1KMT2ASTS | |
| SCHEMBL3639970 | 0.84 | GPR119 (0.56) | ALDH1A1EPHX2MEN1KMT2ASTS | |
| SCHEMBL28457523 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ASTSGPR119 | |
| SCHEMBL27706952 | 0.83 | SIGMAR1 (0.59) | ALDH1A1EPHX2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186921-A1 | AZACYCLIC COMPOUNDS | ACADIA PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2007124136-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186921-A1 | AZACYCLIC COMPOUNDS | HTR6, HTR5A, HNMT | ALDH1A1 1235/4885EPHX2 1938/4885SIGMAR1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.