Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214493 | 0.87 | MAPK14 (0.40) | MAPK14UCHL1CXCR2KMT2A | |
| SCHEMBL396898 | 0.85 | MAPK14 (0.49) | MAPK14PIK3CAUCHL1MAPK13MAPK12 | |
| SCHEMBL4231887 | 0.80 | MAPK14 (0.49) | MAPK14PIK3CAMAPK13MAPK12MAPK11 | |
| SCHEMBL2215153 | 0.77 | HDAC6 (0.41) | MAPK14UCHL1CXCR2MEN1KMT2A | |
| SCHEMBL4225203 | 0.76 | SIRT2 (0.38) | MAPK14PIK3CACXCR2 | |
| SCHEMBL14077643 | 0.75 | SMN1; SMN2 (0.47) | MAPK14RAB9ANPC1MEN1KMT2A | |
| SCHEMBL13948889 | 0.74 | LIPE (0.36) | CXCR2RAB9ANPC1 | |
| SCHEMBL601557 | 0.73 | UCHL1 (0.44) | UCHL1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL20460581 | 0.73 | HDAC6 (0.39) | MAPK14CXCR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20448590 | 0.71 | HDAC1 (0.37) | CXCR2RAB9ADPP4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023725-A1 | Fused Heteroaryl Derivatives for Use as P38 Kinase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2009-01-22 | — | — | US | disclosed |
| US-20090023725-A1 | Fused Heteroaryl Derivatives for Use as P38 Kinase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2009-01-22 | — | — | US | disclosed |
| US-20090023725-A1 | Fused Heteroaryl Derivatives for Use as P38 Kinase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2009-01-22 | — | — | US | disclosed |
| EP-1708996-B1 | FUSED HETEROYRAL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1569039-B1 | Polymeric charge transport compositions for organophotoreceptors | SAMSUNG ELECTRONICS CO LTD (KR) | 2008-08-06 | — | — | EP | disclosed |
| US-7291431-B2 | Organophotoreceptor with charge transport compound having an epoxy group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-11-06 | — | — | US | disclosed |
| EP-1530096-B1 | Organophotoreceptor with a hydrazone polymer charge transport material | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1418469-B1 | Organophotoreceptor with charge transport compound with hydrazone groups | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-04-04 | — | — | EP | disclosed |
| US-7166400-B2 | Organophotoreceptor with a hydrazone polymer charge transport material | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-01-23 | — | — | US | disclosed |
| EP-1465020-B1 | Organophotoreceptor with a charge transport compound having an epoxy group | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-10-18 | — | — | EP | disclosed |
| US-6835514-B2 | Flexible photoreceptors for electrophotography | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-12-28 | — | — | US | disclosed |
| US-6835513-B2 | An organophotoreceptor comprising: (a) a charge transport compound having the formula carbazole compound dispersion of colorant particles in an organic liquid and charge transport compound having the formula of carbazole compound | SAMSUNG ELECTRONIC CO., LTD. (KR) | 2004-12-28 | — | — | US | disclosed |
| EP-1465020-A2 | Organophotoreceptor with a charge transport compound having an epoxy group | Samsung Electronics Co., Ltd. (KR) | 2004-10-06 | — | — | EP | disclosed |
| US-20040161685-A1 | Organophotoreceptor with a charge transport compound having an epoxy group | S-PRINTING SOLUTION CO., LTD. (KR) | 2004-08-19 | — | — | US | disclosed |
| US-20040106054-A1 | Organophotoreceptor with charge transport compound with hydrazone groups | S-PRINTING SOLUTION CO., LTD. (KR) | 2004-06-03 | — | — | US | disclosed |
| EP-1420303-A2 | Organophotoreceptor with charge transport compound having an epoxy group | Samsung Electronics Co., Ltd. (KR) | 2004-05-19 | — | — | EP | disclosed |
| EP-1418469-A2 | Organophotoreceptor with charge transport compound with hydrazone groups | Samsung Electronics Co., Ltd. (KR) | 2004-05-12 | — | — | EP | disclosed |
| US-20040081903-A1 | Organophotoreceptor with charge transport compound having an epoxy group | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2004-04-29 | — | — | US | disclosed |
| US-20030215728-A1 | Hydrazone-based charge transport compounds | S-PRINTING SOLUTION CO., LTD. (KR) | 2003-11-20 | — | — | US | disclosed |
| US-20030207188-A1 | Carbazole based charge transport compounds | S-PRINTING SOLUTION CO., LTD. (KR) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207188-A1 | Carbazole based charge transport compounds | SLC33A1, SLC43A1, AHR | MAPK14 2210/4885PIK3CA 2910/4885UCHL1 4529/4885 |
| US-20090023725-A1 | Fused Heteroaryl Derivatives for Use as P38 Kinase Inhibitors | MAPK1, MAPKAPK2, MAPK7 | MAPK14 19/4885PIK3CA 1271/4885UCHL1 4310/4885 |
| US-20040081903-A1 | Organophotoreceptor with charge transport compound having an epoxy group | SLC43A1, SLC46A1, SLC1A2 | MAPK14 4002/4885PIK3CA 4118/4885UCHL1 4601/4885 |
| US-20030215728-A1 | Hydrazone-based charge transport compounds | SLC9A1, SLC9A2, SLC26A4 | MAPK14 1676/4885PIK3CA 2461/4885UCHL1 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.