SCHEMBL4215664

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4226484	0.95	XDH (0.54)	ACLYBCL2L1BADXDHSLC22A12
	SCHEMBL4222990	0.92	ACLY (0.59)	ACLYAKR1C3AKR1C2GRIK1MAPT
	SCHEMBL4217388	0.92	DCLRE1B (0.53)	ACLYBCL2L1BADXDHSLC22A12
	SCHEMBL4216089	0.90	XDH (0.53)	ACLYXDHSLC22A12AKR1C3AKR1C2
	SCHEMBL4223119	0.89	AKR1C3 (0.60)	ACLYAKR1C3AKR1C2GRIK1MAPT
	SCHEMBL4223004	0.89	XDH (0.50)	ACLYBCL2L1BADXDHSLC22A12
	SCHEMBL4223054	0.89	AKR1C3 (0.59)	ACLYXDHSLC22A12AKR1C3AKR1C2
	SCHEMBL4216624	0.89	GRIK1 (0.58)	ACLYXDHSLC22A12AKR1C3AKR1C2
	SCHEMBL4215681	0.88	GRIK1 (0.54)	ACLYXDHSLC22A12AKR1C3AKR1C2
	SCHEMBL4213884	0.88	MCL1 (0.56)	ACLYXDHSLC22A12AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.