Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 4/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226484 | 0.93 | XDH (0.54) | GRIK1AKR1C3AKR1C2ACLYXDH | |
| SCHEMBL4215664 | 0.89 | ACLY (0.52) | GRIK1AKR1C3AKR1C2ACLYXDH | |
| SCHEMBL4215681 | 0.88 | GRIK1 (0.54) | GRIK1AKR1C3AKR1C2CNR1ACLY | |
| SCHEMBL4216089 | 0.87 | XDH (0.53) | GRIK1AKR1C3AKR1C2ACLYXDH | |
| SCHEMBL4223054 | 0.86 | AKR1C3 (0.59) | GRIK1AKR1C3AKR1C2ACLYXDH | |
| SCHEMBL4222396 | 0.85 | XDH (0.52) | GRIK1AKR1C3AKR1C2ACLYXDH | |
| SCHEMBL4215551 | 0.85 | GRIK1 (0.54) | GRIK1AKR1C3AKR1C2XDHSLC22A12 | |
| SCHEMBL4223753 | 0.84 | CLCN2 (0.56) | GRIK1AKR1C3AKR1C2XDHSLC22A12 | |
| SCHEMBL4224024 | 0.84 | MPO (0.52) | GRIK1AKR1C3AKR1C2XDHSLC22A12 | |
| SCHEMBL4218272 | 0.84 | AKR1C3 (0.61) | AKR1C3AKR1C2ACLYXDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8327467-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| EP-1860098-B1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1860098-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP11, MMP3 | GRIK1 469/4885AKR1C3 105/4885AKR1C2 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.