Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245369 | 0.84 | TSHR (0.37) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4222345 | 0.84 | ADRA1A (0.53) | GPR119MAPTLMNAALDH1A1 | |
| SCHEMBL14591361 | 0.82 | KDM1A (0.47) | GPR119MAPTLMNAALDH1A1SMARCA2 | |
| SCHEMBL14591362 | 0.82 | KDM1A (0.47) | GPR119MAPTLMNAALDH1A1SMARCA2 | |
| SCHEMBL30061913 | 0.78 | DPP4 (0.45) | GPR119MAPTLMNAKITSMARCA2 | |
| SCHEMBL20722901 | 0.78 | DPP4 (0.45) | GPR119MAPTLMNAKITSMARCA2 | |
| SCHEMBL165582 | 0.76 | GPR119 (0.46) | GPR119MAPTLMNAALDH1A1SMARCA2 | |
| SCHEMBL7238644 | 0.74 | ADRB1 (0.44) | — | |
| SCHEMBL28673721 | 0.72 | LMNA (0.46) | GPR119MAPTLMNAALDH1A1SMARCA2 | |
| SCHEMBL29707407 | 0.72 | LMNA (0.46) | GPR119MAPTLMNAALDH1A1SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054453-A1 | Novel Tetralins as 5-HT6 Modulators | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054453-A1 | Novel Tetralins as 5-HT6 Modulators | HTR6, TPH1, HTR1A | GPR119 86/4885MAPT 442/4885LMNA 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.