Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4226561 | 0.79 | RAB9A (0.49) | LMNATP53L3MBTL1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4233867 | 0.79 | POLQ (0.50) | POLQALDH1A1EPHX2PPARGHTT | |
| Trifluoroacetic Acid SCHEMBL4227420 | 0.79 | ALDH1A1 (0.43) | LMNAPOLQATMALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4233596 | 0.79 | KMT2A (0.40) | LMNAPOLQALDH1A1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5098273 | 0.78 | TACR1 (0.45) | LMNAPOLQALDH1A1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4235482 | 0.77 | P2RX7 (0.41) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4223287 | 0.76 | HDAC3 (0.43) | ALDH1A1KMT2AMEN1EPHX2PPARG | |
| Trifluoroacetic Acid SCHEMBL4235529 | 0.75 | KDM4E (0.50) | LMNAATML3MBTL1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4227826 | 0.71 | CACNA2D1 (0.48) | POLQALDH1A1KMT2AMEN1CACNA2D1 | |
| Hydrochloric Acid SCHEMBL4233574 | 0.71 | POLB (0.51) | LMNATP53L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | LMNA 3423/4885TP53 3167/4885POLQ 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.