Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4233867 | 0.85 | POLQ (0.50) | ALDH1A1HTTPOLQEPHX2 | |
| Trifluoroacetic Acid SCHEMBL4227420 | 0.85 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5098273 | 0.84 | TACR1 (0.45) | KMT2AALDH1A1NPC1RAB9ANPSR1 | |
| Trifluoroacetic Acid SCHEMBL4223287 | 0.81 | HDAC3 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5108484 | 0.81 | GPR6 (0.39) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4235529 | 0.81 | KDM4E (0.50) | KMT2AMEN1ALDH1A1POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL4225473 | 0.79 | LMNA (0.45) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4226561 | 0.74 | RAB9A (0.49) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4235482 | 0.72 | P2RX7 (0.41) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4236114 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | KMT2A 1438/4885MEN1 464/4885RIPK1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.