Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4233867 | 0.84 | POLQ (0.50) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4233596 | 0.84 | KMT2A (0.40) | KMT2AALDH1A1RAB9ANPC1POLB | |
| Trifluoroacetic Acid SCHEMBL4227420 | 0.84 | ALDH1A1 (0.43) | KMT2AALDH1A1RAB9ANPC1POLB | |
| Trifluoroacetic Acid SCHEMBL4223287 | 0.81 | HDAC3 (0.43) | TACR1HDAC3HDAC1HDAC2HDAC6 | |
| Trifluoroacetic Acid SCHEMBL4235529 | 0.80 | KDM4E (0.50) | KMT2AALDH1A1POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL4225473 | 0.78 | LMNA (0.45) | KMT2AALDH1A1RAB9ANPC1POLB | |
| Trifluoroacetic Acid SCHEMBL4226722 | 0.77 | CD274 (0.42) | TACR1FFAR1FFAR4HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL4226561 | 0.73 | RAB9A (0.49) | KMT2AALDH1A1RAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL4225285 | 0.72 | ALDH1A1 (0.48) | KMT2AALDH1A1RAB9ANPC1POLB | |
| Trifluoroacetic Acid SCHEMBL4235482 | 0.71 | P2RX7 (0.41) | HDAC8KMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | TACR1 1039/4885FFAR1 1149/4885FFAR4 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.