Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5108484 | 0.91 | GPR6 (0.39) | ALDH1A1HPGDKMT2AHTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL4233867 | 0.85 | POLQ (0.50) | ALDH1A1HTTPOLQKDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL4233596 | 0.85 | KMT2A (0.40) | ALDH1A1KMT2AHTTNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5098273 | 0.84 | TACR1 (0.45) | ALDH1A1KMT2AHTTNPSR1NPC1 | |
| Trifluoroacetic Acid SCHEMBL4235529 | 0.83 | KDM4E (0.50) | ALDH1A1KMT2AGAAMEN1POLB | |
| Trifluoroacetic Acid SCHEMBL4235482 | 0.82 | P2RX7 (0.41) | ALDH1A1KMT2AHTTNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4223287 | 0.81 | HDAC3 (0.43) | ALDH1A1KMT2AHTTNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4225473 | 0.79 | LMNA (0.45) | ALDH1A1HPGDKMT2AHTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL4221829 | 0.78 | KDM4E (0.46) | ALDH1A1HPGDKMT2AHTTGAA | |
| Trifluoroacetic Acid SCHEMBL10698406 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | ALDH1A1 266/4885HPGD 1276/4885KMT2A 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.