Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225596 | 0.85 | KMT2A (0.35) | MAT2ATSHRCNR1CNR2HTT | |
| SCHEMBL4219852 | 0.83 | LMNA (0.35) | MAT2ATSHRCNR1CNR2HTR6 | |
| SCHEMBL4231053 | 0.79 | CXCL8 (0.32) | MAT2ATSHRCNR1CNR2LMNA | |
| SCHEMBL4232907 | 0.74 | EGLN1 (0.40) | CNR1CNR2 | |
| SCHEMBL4219849 | 0.74 | KMT2A (0.45) | TSHRCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL4231674 | 0.73 | LMNA (0.39) | TSHRCNR1CNR2HTR6LMNA | |
| SCHEMBL4232192 | 0.70 | EGLN1 (0.37) | TSHRLMNACYP2C19 | |
| SCHEMBL4229598 | 0.69 | KDM4E (0.34) | CNR1CNR2LMNAALDH1A1 | |
| SCHEMBL4219785 | 0.67 | GLP1R (0.42) | MAT2ATSHRCNR1CNR2LMNA | |
| SCHEMBL4225977 | 0.66 | HSP90AA1 (0.45) | CNR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |