Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232907 | 0.80 | EGLN1 (0.40) | MAPK14CNR1CNR2 | |
| SCHEMBL4232192 | 0.76 | EGLN1 (0.37) | HPGDLMNA | |
| SCHEMBL4225596 | 0.71 | KMT2A (0.35) | ALDH1A1MEN1MAPTKMT2ACNR1 | |
| SCHEMBL4225599 | 0.69 | MAT2A (0.33) | ALDH1A1LMNACNR1CNR2 | |
| SCHEMBL4225977 | 0.68 | HSP90AA1 (0.45) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL4231053 | 0.67 | CXCL8 (0.32) | KMT2ALMNACNR1CNR2 | |
| SCHEMBL4219785 | 0.66 | GLP1R (0.42) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL4231314 | 0.66 | MAPK14 (0.36) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL4219849 | 0.66 | KMT2A (0.45) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27686519 | 0.65 | BCHE (0.41) | KDM4EALDH1A1L3MBTL1POLBPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |