Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 3/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222898 | 0.94 | AKR1C3 (0.51) | AKR1C3AKR1C2HCAR2ACLYCYP3A4 | |
| SCHEMBL4212934 | 0.93 | SIRT2 (0.52) | AKR1C3AKR1C2HCAR2ACLYACMSD | |
| SCHEMBL4223119 | 0.89 | AKR1C3 (0.60) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4223004 | 0.89 | XDH (0.50) | AKR1C3AKR1C2HCAR2MAPTACLY | |
| SCHEMBL4221820 | 0.87 | HNF4A (0.54) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4223666 | 0.86 | SIRT2 (0.61) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4222990 | 0.86 | ACLY (0.59) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4209169 | 0.85 | GRIK1 (0.58) | AKR1C3AKR1C2HCAR2GFERACLY | |
| SCHEMBL4211160 | 0.84 | ACLY (0.60) | AKR1C3AKR1C2HCAR2MAPTGFER | |
| SCHEMBL4222643 | 0.83 | FABP4 (0.56) | AKR1C3AKR1C2HCAR2FABP4ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8327467-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| EP-1860098-B1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1860098-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP11, MMP3 | AKR1C3 105/4885AKR1C2 287/4885HCAR2 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.