SCHEMBL4234069

SCHEMBL4234069

CC1(C)C2CCC(CS)C1C2

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.45
MAPK14 Q16539 1/20 0.45
CAMK1D Q8IU85 1/20 0.45
HDAC6 Q9UBN7 3/20 0.38
TBXA2R P21731 2/20 0.38
EPHX2 P34913 1/20 0.36
CXCR3 P49682 2/20 0.35
OPRM1 P35372 1/20 0.34
OPRK1 P41145 1/20 0.34
OPRL1 P41146 1/20 0.34
ALOX15 P16050 1/20 0.34
S1PR1 P21453 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.31
SCN9A Q15858 4/20 0.30
SCN5A Q14524 1/20 0.30
HSD11B1 P28845 1/20 0.30
OGFRL1 Q5TC84 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702183 1.00 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL3702180 1.00 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL4411047 0.80 RET (0.46) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL14325015 0.78 MAPK14 (0.49) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL8991557 0.78 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL9426196 0.78 RET (0.49) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL8316378 0.78 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL596246 0.78 RET (0.53) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL177080 0.78 MAPK14 (0.49) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL2811047 0.78 MAPK14 (0.49) RETMAPK14CAMK1DHDAC6TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200146960-A1 Antiperspirant and Deodorant Compositions PROCTER & GAMBLE (US) 2020-05-14 US claimed
US-10568825-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2020-02-25 US claimed
US-20170267944-A1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-09-21 US claimed
US-20150322376-A1 Fragrance Compositions THE PROCTER & GAMBLE COMPANY 2015-11-12 US claimed
EP-2931854-A1 FRAGRANCE MATERIALS The Procter & Gamble Company (US) 2015-10-21 EP claimed
US-20140179748-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMPANY (US) 2014-06-26 US claimed
WO-2014093807-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO claimed
US-20140170194-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 US claimed
US-20140170102-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMAPNY (US) 2014-06-19 US claimed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO claimed
US-12636240-B2 Antiperspirant composition COTY INC. (US) 2026-05-26 US disclosed
US-12533302-B2 Systems and methods for delivery of actives and healing tissue VIAS PARTNERS, LLC 2026-01-27 US disclosed
EP-4304548-B1 ANTIPERSPIRANT COMPOSITION COTY INC (US) 2025-07-23 EP disclosed
US-20240299262-A1 ANTIPERSPIRANT COMPOSITION COTY INC. 2024-09-12 US disclosed
US-20240252424-A1 ANTIPERSPIRANT COMPOSITION COTY INC. 2024-08-01 US disclosed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO disclosed
US-5800897-A Air freshener composition containing a fiber pad EASTMAN CHEMICAL COMPANY (US) 1998-09-01 US disclosed
WO-1997026926-A1 AIR FRESHENER COMPOSITION CONTAINING A FIBER PAD EASTMAN CHEMICAL COMPANY (US) 1997-07-31 WO disclosed
US-4283347-A Para-menth-1-ene-7-sulfonic acid and salts thereof SCM CORPORATION (US) 1981-08-11 US disclosed
US-4224240-A Preparation of para-menth-1-ene-7-sulfonate salts and corresponding acids SCM CORPORATION (US) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10568825-B2 Antiperspirant and deodorant compositions DEK, QDPR, GPX4 RET 3101/4885MAPK14 2454/4885CAMK1D 4671/4885
US-20140170102-A1 Antiperspirant and Deodorant Compositions DEK, QDPR, GPX4 RET 3101/4885MAPK14 2454/4885CAMK1D 4671/4885
US-12533302-B2 Systems and methods for delivery of actives and healing tissue EXOSC10, PDGFA, EXOSC9 RET 4145/4885MAPK14 2477/4885CAMK1D 3197/4885
US-20200146960-A1 Antiperspirant and Deodorant Compositions DEK, QDPR, GPX4 RET 3101/4885MAPK14 2454/4885CAMK1D 4671/4885
US-12636240-B2 Antiperspirant composition OPRD1, DRD2, TAS2R40 RET 2770/4885MAPK14 2320/4885CAMK1D 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.