SCHEMBL4236065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4220713	0.89	AQP1 (0.52)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL27703033	0.89	AQP1 (0.47)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4220777	0.89	PRKAB2 (0.47)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4234817	0.89	AQP1 (0.50)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4230249	0.89	AQP1 (0.50)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4222465	0.88	PRKAB2 (0.64)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4225658	0.86	AQP1 (0.50)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4221998	0.84	AQP1 (0.52)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4218760	0.84	AQP1 (0.56)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL4220019	0.83	PRKAB2 (0.58)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.