SCHEMBL423737

SCHEMBL423737

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
CA2 P00918 6/20 0.33
CA1 P00915 5/20 0.32
MMP1 P03956 2/20 0.32
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP8 P22894 2/20 0.32
MMP13 P45452 2/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141002 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL811565 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL428765 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL810417 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL3217875 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL28450248 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL10622506 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL810833 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL159453 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL810923 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775175-A Allyl compound, preparation method thereof, bismaleimide resin composition and application thereof 广东盈骅新材料科技有限公司 2025-04-08 CN claimed
CN-119571631-A High-toughness puncture-resistant tarpaulin material and preparation method thereof 江苏泽昊新材料有限公司 2025-03-07 CN claimed
CN-118359850-B Preparation method and application of ultra-matte high-hardness co-extruded fabric for wood plastic 江苏锐升新材料有限公司 2024-11-29 CN claimed
CN-118788155-A Preparation method of zwitterionic-fluorine functionalized anti-pollution polyamide composite membrane 中国石油大学(华东) 2024-10-18 CN claimed
CN-118161340-B Aqueous humor drainage tube 明澈生物科技(苏州)有限公司 2024-07-05 CN claimed
CN-118161340-A Aqueous humor drainage tube 明澈生物科技(苏州)有限公司 2024-06-11 CN claimed
CN-117297980-A Dental restoration composite material with antibacterial function 北京化工大学 2023-12-29 CN claimed
CN-115960609-B Etching solution for etching oxide layer on surface of wafer with high selectivity, preparation method and application thereof 浙江奥首材料科技有限公司 2023-10-24 CN claimed
CN-114409887-B Fluorinated end group amphiphilic polymer, preparation method and application thereof 浙江大学杭州国际科创中心 2023-09-01 CN claimed
CN-115960609-A Etching solution for etching oxide layer on surface of wafer with high selectivity, preparation method and application thereof 浙江奥首材料科技有限公司 2023-04-14 CN claimed
CN-114409887-A Fluorinated terminal group amphiphilic polymer, and preparation method and application thereof 浙江大学杭州国际科创中心 2022-04-29 CN claimed
CN-119775175-A Allyl compound, preparation method thereof, bismaleimide resin composition and application thereof 广东盈骅新材料科技有限公司 2025-04-08 CN disclosed
CN-119571631-A High-toughness puncture-resistant tarpaulin material and preparation method thereof 江苏泽昊新材料有限公司 2025-03-07 CN disclosed
US-12208159-B2 Compositions, methods and kits for treating a contact lens UNIVERSITY OF HOUSTON SYSTEM (US) 2025-01-28 US disclosed
CN-118359850-B Preparation method and application of ultra-matte high-hardness co-extruded fabric for wood plastic 江苏锐升新材料有限公司 2024-11-29 CN disclosed
EP-0769969-A1 GAS-FILLED MICROSPHERES WITH FLUORINE-CONTAINING SHELLS MOLECULAR BIOSYSTEMS, INC. (US) 1997-05-02 EP disclosed
US-5606973-A CONTRAST MOLECULAR BIOSYSTEMS, INC. (US) 1997-03-04 US disclosed
WO-1996040280-A2 LIQUID CORE MICRODROPLETS FOR ULTRASOUND IMAGING MOLECULAR BIOSYSTEMS, INC. (US) 1996-12-19 WO disclosed
WO-1996040278-A2 GAS-EXCHANGE METHOD OF MAKING GAS-FILLED MICROSPHERES MOLECULAR BIOSYSTEMS, INC. (US) 1996-12-19 WO disclosed
WO-1996004018-A1 GAS-FILLED MICROSPHERES WITH FLUORINE-CONTAINING SHELLS MOLECULAR BIOSYSTEMS, INC. (US) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12208159-B2 Compositions, methods and kits for treating a contact lens F7, PROC, CUTA THRB 2489/4885CA2 964/4885CA1 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.