SCHEMBL4245175

SCHEMBL4245175

Cc1ccc(CC2CCN(C(=O)NC(=O)c3ccc(OCc4ccccc4)cc3)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.58
SCN2A Q99250 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 1/20 0.52
TMEM97 Q5BJF2 1/20 0.52
MAPT P10636 2/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPK1 P28482 1/20 0.51
POLB P06746 1/20 0.51
LTB4R Q15722 1/20 0.50
LTB4R2 Q9NPC1 1/20 0.50
CHRM4 P08173 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4246343 0.94 MEN1 (0.55) FAAHMEN1KMT2ASMN1; SMN2POLB
SCHEMBL4239342 0.92 SMN1; SMN2 (0.63) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL4244741 0.90 SLC6A5 (0.53) MEN1KMT2ASMN1; SMN2POLBLTB4R
SCHEMBL5165692 0.90 ADAMTS5 (0.60) FAAHMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL4251982 0.85 DGAT1 (0.54) FAAHMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL4243510 0.84 FAAH (0.56) FAAHMEN1KMT2ALMNATMEM97
SCHEMBL5182248 0.83 SMN1; SMN2 (0.51) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL4245174 0.83 PARP10 (0.60) FAAHMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL4239616 0.82 FAAH (0.61) FAAHMEN1KMT2APOLB
SCHEMBL4242849 0.81 CHRM4 (0.52) MEN1KMT2ASMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090170901-A1 Benzoyl Urea Derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2009-07-02 US disclosed
EP-1771429-A1 NEW BENZOYL UREA DERIVATIVES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2007-04-11 EP disclosed
WO-2006010966-A1 NEW BENZOYL UREA DERIVATIVES Richter Gedeon Vegyészeti Gyár Rt. (HU) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170901-A1 Benzoyl Urea Derivatives OPRM1, GRIN2C, GRIN3A FAAH 1415/4885SCN2A 184/4885MEN1 4432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.