SCHEMBL424552

SCHEMBL424552

Cc1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
TDP1 Q9NUW8 3/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.39
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
HDAC4 P56524 1/20 0.38
MEN1 O00255 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 2/20 0.37
CYP2C19 P33261 1/20 0.37
NFKB1 P19838 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054644 0.91 ACHE (0.43) ACHELMNATSHRALOX12TDP1
SCHEMBL29973455 0.91 ACHE (0.43) ACHELMNATSHRALOX12TDP1
SCHEMBL31329266 0.91 ACHE (0.43) ACHELMNATSHRALOX12TDP1
Toliodium SCHEMBL125171 0.88 ACHE (0.57) ACHELMNATSHRALOX12TDP1
SCHEMBL17200747 0.87 ACHE (0.40) ACHELMNATSHRALOX12TDP1
Toliodium SCHEMBL3284569 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Toliodium SCHEMBL5408779 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Toliodium SCHEMBL9296014 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Toliodium SCHEMBL7743288 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
SCHEMBL12762155 0.85 ALDH1A1 (0.38) ACHELMNATSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6498200-B1 OXIRANE OR OXETANE RING COMPOUND, ORGANIC PEROXIDE, ONIUM SALT CATALYST, AND ALKALINE FILLER; CURES RAPIDLY; STABLE DOES NOT CAUSE INCREASE IN ELECTROCONDUCTIVITY OR CORROSION; SEALANT, BINDER, ENCAPSULATING AGENT, DIELECTRIC FILM NAMICS CORPORATION (JP) 2002-12-24 US claimed
US-11914294-B2 Positive resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-27 US disclosed
US-11883510-B2 Dental composition comprising a particulate carrier supporting a coinitiator DENTSPLY SIRONA INC. (US) 2024-01-30 US disclosed
US-20240027909-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240027909-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-11860540-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-02 US disclosed
US-11860540-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-02 US disclosed
US-11844848-B2 Photocurable dental composition DENTSPLY SIRONA INC. (US) 2023-12-19 US disclosed
US-20230400770-A1 Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
US-4607116-A FROM DIARYLIODONIUM SALT NIPPON PETROCHEMICALS COMPANY LIMITED (JP) 1986-08-19 US disclosed
EP-0119065-B1 PROCESS FOR PREPARING DIARYLS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-08-13 EP disclosed
US-4590281-A REACTING DIARYLIODONIUM SALT WITH UNSATURATED ALCOHOL NIPPON PETROCHEMICALS COMPANY (JP) 1986-05-20 US disclosed
EP-0061898-B1 VISIBLE LIGHT SENSITIVE, THERMALLY DEVELOPABLE IMAGING SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-19 EP disclosed
EP-0119068-A1 Method for preparing diaryl iodonium salts NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-09-19 EP disclosed
EP-0119065-A1 Process for preparing diaryls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-09-19 EP disclosed
EP-0119067-A1 Process for preparing aldehydes NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-09-19 EP disclosed
US-4460677-A Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
US-4386154-A ACYLATED LEUCO DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-31 US disclosed
EP-0061898-A1 Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844848-B2 Photocurable dental composition TST, SULT1A1, SULT2A1 ACHE 3573/4885LMNA 3664/4885TSHR 4613/4885
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 ACHE 4873/4885LMNA 1159/4885TSHR 2364/4885
US-11883510-B2 Dental composition comprising a particulate carrier supporting a coinitiator PICALM, PDS5B, CLTA ACHE 3568/4885LMNA 3551/4885TSHR 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.