Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653982 | 0.84 | KDM4E (0.37) | ALDH1A1HPGDKDM4EHSD17B10MAPK1 | |
| SCHEMBL13658750 | 0.84 | PTGDR2 (0.42) | KDM4EHSD17B10TSHRCYP1A2NPSR1 | |
| SCHEMBL14106835 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4ETSHRMAPTLMNA | |
| SCHEMBL2250872 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL29843932 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL9507379 | 0.78 | USP2 (0.57) | ALDH1A1HPGDKDM4EUSP2MAPK1 | |
| SCHEMBL4798661 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2251583 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL5178820 | 0.77 | ESR1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL1417291 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247781-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090247781-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090247781-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-7402692-B2 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7396954-B2 | Intermediates in producing phenoxyacetic acid preventives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7393968-B2 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20080045741-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| US-20080045740-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID PREVENTIVES AND METHOD OF USING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| US-20080045739-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME | KISSEI PHARMACEUTICAL CO., LTD (JP) | 2008-02-21 | — | — | US | disclosed |
| US-7329771-B2 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same | KISSEI PHARMACEUTICALS CO., LTD. (JP) | 2008-02-12 | — | — | US | disclosed |
| EP-1809591-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-20070088174-A1 | Synthesis of phenoxyacetic acid derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| US-20070088174-A1 | Synthesis of phenoxyacetic acid derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| US-20070088174-A1 | Synthesis of phenoxyacetic acid derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| US-20060135605-A1 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| WO-2006045519-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | KISSEI PHARMACEUTICAL CO., LTD. (GB) | 2006-05-04 | — | — | WO | disclosed |
| EP-1535897-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088174-A1 | Synthesis of phenoxyacetic acid derivatives | DDC, PAH, HPD | ALDH1A1 5/4885HPGD 298/4885KDM4E 422/4885 |
| US-20060135605-A1 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same | ADRB3, ADRA1A, PAH | ALDH1A1 304/4885HPGD 1381/4885KDM4E 2697/4885 |
| US-20080045739-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME | ADRB3, ADRA1A, PAH | ALDH1A1 304/4885HPGD 1381/4885KDM4E 2697/4885 |
| US-20090247781-A1 | SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES | DDC, PAH, HPD | ALDH1A1 7/4885HPGD 308/4885KDM4E 414/4885 |
| US-20080045740-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID PREVENTIVES AND METHOD OF USING THE SAME | ADRB3, PAH, SLC10A2 | ALDH1A1 228/4885HPGD 1251/4885KDM4E 3001/4885 |
| US-20080045741-A1 | INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME | ADRB3, ADRA1A, PAH | ALDH1A1 304/4885HPGD 1381/4885KDM4E 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.