Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 5/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9926464 | 0.84 | P2RX7 (0.51) | P2RX7GALR3NR2F2 | |
| SCHEMBL4709927 | 0.84 | P2RX7 (0.48) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL8204517 | 0.83 | ERCC1 (0.54) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL8424664 | 0.83 | ERCC1 (0.61) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL13329827 | 0.83 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL9523440 | 0.82 | ALDH1A1 (0.65) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL30545006 | 0.82 | ALDH1A1 (0.65) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL8233977 | 0.81 | KDM4E (0.62) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL12366792 | 0.81 | RECQL (0.55) | ERCC1ERCC4P2RX7GALR3NR2F2 | |
| SCHEMBL3874153 | 0.81 | HIF1A (0.58) | ERCC1ERCC4KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| EP-3016950-B1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-06-07 | — | — | EP | disclosed |
| US-9663529-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663529-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160152627-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-06-02 | — | — | US | disclosed |
| US-20160152627-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-06-02 | — | — | US | disclosed |
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152627-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | MYLK, MYLK2, ROCK1 | ERCC1 3605/4885ERCC4 3343/4885P2RX7 1041/4885 |
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | PYCR1, COX5A, COX5B | ERCC1 4042/4885ERCC4 4690/4885P2RX7 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.