Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.59 |
| ▸ | NOS1 | P29475 | 3/20 | 0.59 |
| ▸ | NOS2 | P35228 | 3/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637605 | 1.00 | NOS3 (0.59) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL42487 | 1.00 | NOS3 (0.59) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL30440587 | 1.00 | NOS3 (0.59) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL668476 | 1.00 | NOS3 (0.59) | NOS3NOS1NOS2SLC7A5PKM | |
| Hydrochloric Acid SCHEMBL4422373 | 0.98 | NOS3 (0.58) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL29155392 | 0.88 | SLC7A5 (0.55) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL31370153 | 0.87 | PKM (0.58) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL29475631 | 0.87 | PKM (0.58) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL1527683 | 0.87 | PKM (0.58) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL1527682 | 0.87 | PKM (0.58) | NOS3NOS1NOS2SLC7A5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11674136-B2 | DNA-templated macrocycle library | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-13 | — | — | US | disclosed |
| US-11674136-B2 | DNA-templated macrocycle library | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-13 | — | — | US | disclosed |
| US-11674136-B2 | DNA-templated macrocycle library | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| CN-107709334-B | Novel amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-04-13 | — | — | CN | disclosed |
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-24 | — | — | US | disclosed |
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-24 | — | — | US | disclosed |
| US-10457687-B2 | Aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2019-10-29 | — | — | US | disclosed |
| WO-2019168654-A9 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-10-17 | — | — | WO | disclosed |
| US-20190031675-A1 | AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2019-01-31 | — | — | US | disclosed |
| EP-3313850-B1 | NEW AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2018-10-03 | — | — | EP | disclosed |
| EP-1890684-B1 | Treatment of sleep-wake disorders | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-14 | — | — | EP | disclosed |
| EP-2590645-A2 | METHODS FOR TREATING BIPOLAR DISORDER | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012002687-A2 | METHODS FOR TREATING BIPOLAR DISORDER | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11674136-B2 | DNA-templated macrocycle library | IDE, IAPP, POLRMT | NOS3 3172/4885NOS1 3557/4885NOS2 3753/4885 |
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | IDE, IAPP, POLRMT | NOS3 3172/4885NOS1 3557/4885NOS2 3753/4885 |
| US-20190031675-A1 | AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAX, ARG2, ANXA5 | NOS3 569/4885NOS1 388/4885NOS2 196/4885 |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | NOS3 2841/4885NOS1 1185/4885NOS2 2556/4885 |
| US-10457687-B2 | Aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them | BAX, ARG2, ANXA5 | NOS3 569/4885NOS1 388/4885NOS2 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.