SCHEMBL4248977

SCHEMBL4248977

CCCCOOCC(O)CO

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.57
LMNA P02545 2/20 0.46
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
DGKA P23743 1/20 0.39
TSHR P16473 1/20 0.38
FAAH O00519 2/20 0.37
HTT P42858 1/20 0.37
PLA2G2C Q5R387 1/20 0.36
ALDH1A1 P00352 3/20 0.33
AR P10275 1/20 0.33
CNR2 P34972 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27710759 0.94 USP2 (0.66) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL113021 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL20743365 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL28115449 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL14714348 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL344684 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL26496284 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL1752698 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL93726 0.92 USP2 (0.69) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL6015046 0.89 USP2 (0.42) USP2LMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN claimed
EP-2810564-B1 Sensation masking composition TAKASAGO INT CORP (USA) (US) 2017-06-14 EP claimed
EP-1639072-A1 SOLVENT TREATMENT OF FABRIC ARTICLES The Procter & Gamble Company (US) 2006-03-29 EP claimed
US-20050223500-A1 Solvent treatment of fabric articles THE PROCTER & GAMBLE COMPANY 2005-10-13 US claimed
WO-2005003278-A1 SOLVENT TREATMENT OF FABRIC ARTICLES THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 WO claimed
US-20260034046-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING CATIONIC SURFACTANT AND FATTY ALCOHOL L'OREAL (FR) 2026-02-05 US disclosed
US-20260000602-A1 ANHYDROUS HAIR TREATMENT COMPOSITION L'OREAL (FR) 2026-01-01 US disclosed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP disclosed
EP-3510010-B1 TASTE MODULATING ALDEHYDE TAKASAGO PERFUMERY CO LTD (JP) 2023-09-06 EP disclosed
US-11540542-B2 Taste modulating aldehydes TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-01-03 US disclosed
CN-109996778-B Taste modifying aldehydes 高砂香料工业株式会社 2022-12-13 CN disclosed
EP-3984599-A1 ENHANCED PERFUME COMPOSITIONS Takasago International Corporation (JP) 2022-04-20 EP disclosed
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-08-20 US disclosed
CN-101218222-A Vanillin acetals and sensory stimulant composition containing the same TAKASAGO PERFUMERY CO LTD (JP) 2008-07-09 CN disclosed
EP-1902043-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME Takasago International Corporation (JP) 2008-03-26 EP disclosed
WO-2007004740-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-01-11 WO disclosed
US-20060269500-A1 Topical warming composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-11-30 US disclosed
CN-85108027-A Spray and Emulsion that oral fine looses 1986-07-16 CN disclosed
EP-0180483-A2 Oral fine dispersions sprays and emulsions ADVANCED ORAL HEALTHCORP LIMITED (CA) 1986-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11540542-B2 Taste modulating aldehydes TAS2R10, TAS2R50, TAS2R1 USP2 4146/4885LMNA 4718/4885KDM4E 2218/4885
US-20060269500-A1 Topical warming composition CUTA, NACA, LSM14A USP2 4194/4885LMNA 1435/4885KDM4E 2963/4885
US-20260000602-A1 ANHYDROUS HAIR TREATMENT COMPOSITION TAS2R40, BRDT, APOB USP2 4212/4885LMNA 1502/4885KDM4E 2035/4885
US-20260034046-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING CATIONIC SURFACTANT AND FATTY ALCOHOL KRT18, DSG1, PRKDC USP2 4278/4885LMNA 586/4885KDM4E 767/4885
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TRPA1, TRPV1, TAS2R5 USP2 1643/4885LMNA 3990/4885KDM4E 1157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.