Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.43 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.43 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975794 | 0.98 | CHRM5 (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL718779 | 0.87 | ACHE (0.50) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1568811 | 0.84 | ACHE (0.52) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL976265 | 0.83 | ACHE (0.45) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL6550800 | 0.79 | BLM (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7093817 | 0.76 | ACHE (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL8501382 | 0.75 | CHRM5 (0.50) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL7765956 | 0.74 | ACHE (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1974755 | 0.74 | ACHE (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7791560 | 0.74 | ACHE (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017092951-A1 | DOMAIN PARTICLES OF PESTICIDE PARTICLES EMBEDDED IN AN IONIC ACRYLATE COPOLYMER | BASF SE (DE) | 2017-06-08 | — | — | WO | claimed |
| US-10604685-B2 | Aqueous polymer dispersions for composite film lamination | BASF SE (DE) | 2020-03-31 | — | — | US | disclosed |
| US-10420339-B2 | Aqueous fungicidal composition and use thereof for combating harmful micro organisms | BASF SE (DE) | 2019-09-24 | — | — | US | disclosed |
| US-20180118985-A1 | AQUEOUS POLYMER DISPERSIONS FOR COMPOSITE FILM LAMINATION | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| WO-2017092951-A1 | DOMAIN PARTICLES OF PESTICIDE PARTICLES EMBEDDED IN AN IONIC ACRYLATE COPOLYMER | BASF SE (DE) | 2017-06-08 | — | — | WO | disclosed |
| US-20170112124-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICRO ORGANISMS | BASF SE (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20140234425-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | BASF SE (DE) | 2014-08-21 | — | — | US | disclosed |
| US-8778645-B2 | Method for the production of glutaconate | BASF SE (DE) | 2014-07-15 | — | — | US | disclosed |
| US-8741968-B2 | Aqueous fungicidal composition and use thereof for combating harmful microorganisms | BASF AKTIENGESELLSCHAFT (DE) | 2014-06-03 | — | — | US | disclosed |
| US-20120309897-A1 | Polymers containing heterocyclic 3-ring compounds and iodine-containing compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120053283-A1 | POLYMER ADDITIVES CONTAINING PARTICLES | BASF SE (DE) | 2012-03-01 | — | — | US | disclosed |
| US-20120021472-A1 | Method for the Production of Glutaconate | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| EP-2387614-A2 | METHOD FOR THE PRODUCTION OF GLUTACONATE | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-20110257340-A1 | Process for Producing Water-Absorbing Polymer Particles | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
| US-8037635-B1 | Frog fishing lure system | WYATT CHRISTOPHER A | 2011-10-18 | — | — | US | disclosed |
| US-20100273897-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | GOETTSCHE REIMER | 2010-10-28 | — | — | US | disclosed |
| WO-2010081885-A2 | METHOD FOR THE PRODUCTION OF GLUTACONATE | BASF SE (DE) | 2010-07-22 | — | — | WO | disclosed |
| US-20100166985-A1 | AQUEOUS DISPERSIONS OF (METH)ACRYLIC ESTERS OF POLYMERS COMPRISING N-HYDROXYALKYLATED LACTAM UNITS AND USE OF (METH)ACRYLIC ESTERS OF POLYMERS COMPRISING N-HYDROXYALKYLATED LACTAM UNITS | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20090318605-A1 | POLYMER ADDITIVES CONTAINING PARTICLES | BASF SE (DE) | 2009-12-24 | — | — | US | disclosed |
| US-20080090886-A1 | Comprising fungicidal organic active substance with solubility in water of not more than 5 g/l at 25 degrees C./1013 mbar, and finely-divided ethylenically unsaturated polymer with particle sizes of not more than 300 nm, in which polymer particles comprise active substance; wood protection | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112124-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICRO ORGANISMS | C1R, MGAM, MYO1G | CHRM1 10/4885CHRM3 65/4885CHRM2 34/4885 |
| US-20140234425-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | C1R, MGAM, CHRM1 | CHRM1 3/4885CHRM3 35/4885CHRM2 25/4885 |
| US-10420339-B2 | Aqueous fungicidal composition and use thereof for combating harmful micro organisms | C1R, MGAM, MYO1G | CHRM1 10/4885CHRM3 65/4885CHRM2 34/4885 |
| US-20080090886-A1 | Comprising fungicidal organic active substance with solubility in water of not more than 5 g/l at 25 degrees C./1013 mbar, and finely-divided ethylenically unsaturated polymer with particle sizes of not more than 300 nm, in which polymer particles comprise active substance; wood protection | C1R, MGAM, CD68 | CHRM1 6/4885CHRM3 45/4885CHRM2 35/4885 |
| US-20120309897-A1 | Polymers containing heterocyclic 3-ring compounds and iodine-containing compounds | TPO, BRD4, SSTR3 | CHRM1 4617/4885CHRM3 3845/4885CHRM2 4814/4885 |
| US-20100273897-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | C1R, MGAM, CHRM1 | CHRM1 3/4885CHRM3 35/4885CHRM2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.