Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 4/20 | 0.42 |
| ▸ | RGS8 | P57771 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726148 | 0.93 | TNF (0.47) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL4810587 | 0.93 | TNF (0.47) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL7321782 | 0.89 | ADORA2A (0.46) | L3MBTL1LMNAADORA2APDE4APDE4B | |
| SCHEMBL4251917 | 0.87 | PDE4A (0.46) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL8175084 | 0.84 | ADORA2A (0.48) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL5687930 | 0.79 | PDE4A (0.47) | LMNAADORA2APDE4APDE4BPDE4C | |
| SCHEMBL3981817 | 0.77 | ADORA2B (0.46) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL3979483 | 0.76 | ADORA2B (0.45) | CCR6L3MBTL1LMNAADORA2APDE4A | |
| SCHEMBL4811164 | 0.76 | ALDH1A1 (0.60) | L3MBTL1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL4255826 | 0.75 | CASP6 (0.46) | CCR6L3MBTL1LMNAADORA2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209561-A1 | Xanthine Derivatives with HM74A Receptor Activity | HATLEY RICHARD JONATHAN DANIEL | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209561-A1 | Xanthine Derivatives with HM74A Receptor Activity | XDH, HCAR1, GPR84 | CCR6 996/4885L3MBTL1 3486/4885LMNA 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.