Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663375 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL1928731 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL4665144 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL3339295 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL3777627 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL436730 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL4665045 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL4663096 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL440049 | 1.00 | LMNA (0.36) | LMNATHRBCA1CA2MMP1 | |
| SCHEMBL3782809 | 0.97 | THRB (0.32) | LMNATHRBKDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009104785-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |