SCHEMBL436730

SCHEMBL436730

OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663375 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL1928731 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665144 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3339295 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3777627 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4259397 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665045 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4663096 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL440049 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3782809 0.97 THRB (0.32) LMNATHRBKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115188851-B Weather-resistant polyester film for solar back plate 苏州易昇光学材料股份有限公司 2022-12-02 CN claimed
CN-115188851-A Weather-resistant polyester film for solar back plate 苏州易昇光学材料股份有限公司 2022-10-14 CN claimed
CN-114032017-B Modified branched fluorinated polyurethane-based polyurethane wire enamel composition with high breakdown voltage and long service life and preparation method thereof 北京理工大学 2022-07-05 CN claimed
CN-114032017-A Modified branched fluorinated polyurethane-based polyurethane wire enamel composition with high breakdown voltage and long service life and preparation method thereof 北京理工大学 2022-02-11 CN claimed
US-6764984-B2 CONTAINING FLUORINATION DITHIOPHOSPHONATE SALT E. I. DU PONT DE NEMOURS AND COMPANY 2004-07-20 US claimed
US-20030139300-A1 Fluorinated lubricant additives BEATTY RICHARD P (US) 2003-07-24 US claimed
WO-1999024016-A1 EMULSIONS FOR AEROSOLIZATION AND DRUG DELIVERY SONUS PHARMACEUTICALS, INC. (US) 1999-05-20 WO claimed
US-5049213-A High energy THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-09-17 US claimed
CN-111278357-B Synthetic film composition comprising polyurethane and polyoxazoline 帝斯曼知识产权资产管理有限公司 2023-10-31 CN disclosed
CN-116848162-A Fluorine-containing polymer 中央硝子株式会社 2023-10-03 CN disclosed
CN-115697254-A Medical implant for cartilage replacement and method for producing such an implant 帝斯曼知识产权资产管理有限公司 2023-02-03 CN disclosed
CN-115667344-A Polymer composition and method for manufacturing medical implant 马斯特里赫特大学医学中心 2023-01-31 CN disclosed
CN-115634312-A Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2023-01-24 CN disclosed
CN-115188851-B Weather-resistant polyester film for solar back plate 苏州易昇光学材料股份有限公司 2022-12-02 CN disclosed
US-5049213-A High energy THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-09-17 US disclosed
US-4965159-A CORE, LAYER FOR CONTROLLING TRIBOELECTRIC CHARGING, AND FLUORINATED ALKYL METHACRYLATE KONICA CORPORATION (JP) 1990-10-23 US disclosed
EP-0354077-A1 Non-centrally symmetric liquid crystals for non-linear optics THOMSON-CSF (FR) 1990-02-07 EP disclosed
US-4508916-A Curable substituted urethane acrylates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-02 US disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3965148-A OIL AND WATER REPELLENT INTERMEDIATE CIBA-GEIGY CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139300-A1 Fluorinated lubricant additives DSG1, FLNA, DGKI LMNA 4820/4885THRB 2127/4885CA1 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.