SCHEMBL3339295

SCHEMBL3339295

OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663375 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL1928731 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665144 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3777627 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4259397 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL436730 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665045 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4663096 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL440049 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3782809 0.97 THRB (0.32) LMNATHRBKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111792985-A Fluorine-containing heat transfer fluid and preparation method and application thereof 北京宇极科技发展有限公司 2020-10-20 CN claimed
CN-111278357-B Synthetic film composition comprising polyurethane and polyoxazoline 帝斯曼知识产权资产管理有限公司 2023-10-31 CN disclosed
CN-115989005-A Polyurethane composite sheet, method for producing a composite sheet and use thereof for producing medical implants 帝斯曼知识产权资产管理有限公司 2023-04-18 CN disclosed
CN-115697254-A Medical implant for cartilage replacement and method for producing such an implant 帝斯曼知识产权资产管理有限公司 2023-02-03 CN disclosed
CN-115667344-A Polymer composition and method for manufacturing medical implant 马斯特里赫特大学医学中心 2023-01-31 CN disclosed
CN-115634312-A Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2023-01-24 CN disclosed
CN-113518633-B Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2022-11-18 CN disclosed
CN-113490516-B Method for preparing composite biological textile and medical implant comprising composite biological textile 帝斯曼知识产权资产管理有限公司 2022-11-08 CN disclosed
CN-113518634-B Radiopaque medical assemblies and devices 帝斯曼知识产权资产管理有限公司 2022-09-27 CN disclosed
CN-111148776-B Synthetic film compositions comprising polyurethane blends 帝斯曼知识产权资产管理有限公司 2022-06-03 CN disclosed
US-20100022730-A1 POLYMERIZABLE COMPOUND HAVING ADAMANTANE STRUCTURE, PROCESS FOR PRODUCTION OF THE SAME, AND RESIN COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2010-01-28 US disclosed
US-7524789-B2 Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-28 US disclosed
EP-2048128-A1 POLYMERIZABLE COMPOUND HAVING ADAMANTANE STRUCTURE, PROCESS FOR PRODUCTION OF THE SAME, AND RESIN COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2009-04-15 EP disclosed
US-20080153982-A1 Vinyl-Thiocarbonate and Polyol Containing Block Copolymers LUBRIZOL ADVANCED MATERIALS, INC. 2008-06-26 US disclosed
US-6297308-B1 Chemical compositions 3M INNOVATIVE PROPERTIES COMPANY 2001-10-02 US disclosed
WO-2001027235-A1 PROCESSES FOR REMOVING WATER FROM THE SURFACE OF A SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-04-19 WO disclosed
EP-0536200-B1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS MINNESOTA MINING & MFG (US) 1995-10-11 EP disclosed
EP-0536200-A1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS. MINNESOTA MINING & MFG (US) 1993-04-14 EP disclosed
US-5087672-A Lower birefringence and viscosity, increased hydrophobicity MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-11 US disclosed
WO-1991019773-A1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022730-A1 POLYMERIZABLE COMPOUND HAVING ADAMANTANE STRUCTURE, PROCESS FOR PRODUCTION OF THE SAME, AND RESIN COMPOSITION ADAM9, ADAM17, PADI1 LMNA 762/4885THRB 4647/4885CA1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.