SCHEMBL4663096

SCHEMBL4663096

OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663375 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL1928731 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665144 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3339295 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3777627 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4259397 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL436730 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665045 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL440049 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3782809 0.97 THRB (0.32) LMNATHRBKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN claimed
CN-107930542-B Micro-fluidic technology for continuously preparing calcium alginate microgel by one-step method 深圳华诺生物科技有限公司 2020-11-20 CN claimed
WO-2004024790-A1 'COPOLYMER, COATING COMPOSITION COMPRISING THE SAME, PROCESS FOR APPLYING IT' ESETEC INCORPORATED (CA) 2004-03-25 WO claimed
CN-118276203-A Preparation method of anti-reflection component and display device 深圳市华星光电半导体显示技术有限公司 2024-07-02 CN disclosed
CN-116745239-A composite particles TDK株式会社 2023-09-12 CN disclosed
CN-115697254-A Medical implant for cartilage replacement and method for producing such an implant 帝斯曼知识产权资产管理有限公司 2023-02-03 CN disclosed
CN-115667344-A Polymer composition and method for manufacturing medical implant 马斯特里赫特大学医学中心 2023-01-31 CN disclosed
CN-113524815-B Waterproof elastic fabric and preparation method thereof 上海沙驰服饰有限公司 2022-07-15 CN disclosed
CN-110799559-B Resin, resin composition, nonwoven fabric, fiber product, separator, secondary battery, electric double layer capacitor, and method for producing nonwoven fabric 东丽株式会社 2022-04-29 CN disclosed
CN-114160750-A Warm core box binder and application method thereof 金耐源(河南)工业科技有限公司 2022-03-11 CN disclosed
CN-113524815-A Waterproof elastic fabric and preparation method thereof 上海沙驰服饰有限公司 2021-10-22 CN disclosed
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN disclosed
CN-112538025-A Preparation method of fluorine-containing compound for hydrophobic surface treatment agent 湖北福力德鞋业有限责任公司 2021-03-23 CN disclosed
CN-107930542-B Micro-fluidic technology for continuously preparing calcium alginate microgel by one-step method 深圳华诺生物科技有限公司 2020-11-20 CN disclosed
CN-110799559-A Resin, resin composition, nonwoven fabric, fiber product, separator, secondary battery, electric double layer capacitor, and method for producing nonwoven fabric 东丽株式会社 2020-02-14 CN disclosed
US-20080153982-A1 Vinyl-Thiocarbonate and Polyol Containing Block Copolymers LUBRIZOL ADVANCED MATERIALS, INC. 2008-06-26 US disclosed
WO-2004024790-A1 'COPOLYMER, COATING COMPOSITION COMPRISING THE SAME, PROCESS FOR APPLYING IT' ESETEC INCORPORATED (CA) 2004-03-25 WO disclosed
US-5929201-A A POLYAMIC ACID IS THE REACTION PRODUCT OF A FLUORINATED MONOAMINE, A DIAMINE AND ATLEAST ONE TETERACARBOXYLIC DIANHYDRIDE ELSICON, INC. (US) 1999-07-27 US disclosed
US-4167546-A Adhesive composition KORSHAK VASILY V 1979-09-11 US disclosed