SCHEMBL4665144

SCHEMBL4665144

OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663375 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL1928731 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3339295 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3777627 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4259397 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL436730 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665045 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4663096 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL440049 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3782809 0.97 THRB (0.32) LMNATHRBKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109989295-B Anhydrous nano deacidification liquid and preparation method thereof 鼎纳科技有限公司 2022-10-25 CN claimed
CN-114437585-A Writing pen ink for files and preparation method thereof 鼎纳科技有限公司 2022-05-06 CN claimed
CN-109321133-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2022-02-11 CN claimed
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN claimed
CN-109370426-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2020-12-22 CN claimed
CN-107930542-B Micro-fluidic technology for continuously preparing calcium alginate microgel by one-step method 深圳华诺生物科技有限公司 2020-11-20 CN claimed
CN-108373540-B Preparation method of fluorine-containing amphiphilic polyacrylic acid block copolymer micelle, obtained product and application 济南大学 2020-07-07 CN claimed
CN-109989295-B Anhydrous nano deacidification liquid and preparation method thereof 鼎纳科技有限公司 2022-10-25 CN disclosed
CN-114437585-A Writing pen ink for files and preparation method thereof 鼎纳科技有限公司 2022-05-06 CN disclosed
CN-109321133-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2022-02-11 CN disclosed
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN disclosed
CN-109096915-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-04-20 CN disclosed
CN-112538025-A Preparation method of fluorine-containing compound for hydrophobic surface treatment agent 湖北福力德鞋业有限责任公司 2021-03-23 CN disclosed
CN-108373540-B Preparation method of fluorine-containing amphiphilic polyacrylic acid block copolymer micelle, obtained product and application 济南大学 2020-07-07 CN disclosed
EP-2099408-B1 FLUOROPOLYMER-BASED EMULSIONS FOR THE INTRAVENOUS DELIVERY OF FLUORINATED VOLATILE ANESTHETICS WISCONSIN ALUMNI RES FOUND (US) 2016-10-05 EP disclosed
US-9000048-B2 Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-04-07 US disclosed
US-20080234389-A1 FLUOROPOLYMER-BASED EMULSIONS FOR THE INTRAVENOUS DELIVERY OF FLUORINATED VOLATILE ANESTHETICS WISCONSIN ALUMNI RESEARCH FOUNDATION 2008-09-25 US disclosed
US-20080153982-A1 Vinyl-Thiocarbonate and Polyol Containing Block Copolymers LUBRIZOL ADVANCED MATERIALS, INC. 2008-06-26 US disclosed
US-7390901-B2 Fluorinated dyes or colorants and their uses SIPIX IMAGING, INC. (US) 2008-06-24 US disclosed
US-20050039274-A1 Fluorinated dyes or colorants and their uses E INK CALIFORNIA, LLC 2005-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234389-A1 FLUOROPOLYMER-BASED EMULSIONS FOR THE INTRAVENOUS DELIVERY OF FLUORINATED VOLATILE ANESTHETICS VHL, FABP3, FABP4 LMNA 3947/4885THRB 3498/4885CA1 254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.