SCHEMBL4663375

SCHEMBL4663375

OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928731 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665144 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3339295 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3777627 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4259397 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL436730 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4665045 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL4663096 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL440049 1.00 LMNA (0.36) LMNATHRBCA1CA2MMP1
SCHEMBL3782809 0.97 THRB (0.32) LMNATHRBKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN claimed
CN-111278357-B Synthetic film composition comprising polyurethane and polyoxazoline 帝斯曼知识产权资产管理有限公司 2023-10-31 CN disclosed
CN-115989005-A Polyurethane composite sheet, method for producing a composite sheet and use thereof for producing medical implants 帝斯曼知识产权资产管理有限公司 2023-04-18 CN disclosed
CN-115697254-A Medical implant for cartilage replacement and method for producing such an implant 帝斯曼知识产权资产管理有限公司 2023-02-03 CN disclosed
CN-115667344-A Polymer composition and method for manufacturing medical implant 马斯特里赫特大学医学中心 2023-01-31 CN disclosed
CN-115634312-A Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2023-01-24 CN disclosed
CN-113518633-B Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2022-11-18 CN disclosed
CN-113490516-B Method for preparing composite biological textile and medical implant comprising composite biological textile 帝斯曼知识产权资产管理有限公司 2022-11-08 CN disclosed
CN-113518634-B Radiopaque medical assemblies and devices 帝斯曼知识产权资产管理有限公司 2022-09-27 CN disclosed
CN-111148776-B Synthetic film compositions comprising polyurethane blends 帝斯曼知识产权资产管理有限公司 2022-06-03 CN disclosed
CN-113518633-A Medical implant assembly comprising composite biological textile and method of manufacture 帝斯曼知识产权资产管理有限公司 2021-10-19 CN disclosed
CN-113518634-A Radiopaque medical assemblies and devices 帝斯曼知识产权资产管理有限公司 2021-10-19 CN disclosed
CN-113490516-A Method for preparing composite biological textile and medical implant comprising composite biological textile 帝斯曼知识产权资产管理有限公司 2021-10-08 CN disclosed
CN-110152507-B Preparation method of self-cleaning polymer porous membrane with surface grafted with mixed polymer brush 闽江学院 2021-07-27 CN disclosed
CN-111971330-A Modified porous polyolefin film and production method thereof 帝斯曼知识产权资产管理有限公司 2020-11-20 CN disclosed
CN-111278358-A Synthetic membrane compositions comprising fluorinated polyurethanes 帝斯曼知识产权资产管理有限公司 2020-06-12 CN disclosed
CN-111278357-A Synthetic membrane compositions comprising polyurethane and polyoxazoline 帝斯曼知识产权资产管理有限公司 2020-06-12 CN disclosed
CN-111148776-A Synthetic film compositions comprising polyurethane blends 帝斯曼知识产权资产管理有限公司 2020-05-12 CN disclosed
US-20080153982-A1 Vinyl-Thiocarbonate and Polyol Containing Block Copolymers LUBRIZOL ADVANCED MATERIALS, INC. 2008-06-26 US disclosed