Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 8/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263388 | 0.87 | PIK3R1 (0.49) | PIK3R1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL3247231 | 0.85 | PIK3R1 (0.42) | PIK3R1PIK3CAADORA2ACSNK1A1CSNK1D | |
| SCHEMBL4256782 | 0.85 | PIK3R1 (0.42) | PIK3R1PIK3CAADORA2ACSNK1A1CSNK1D | |
| SCHEMBL4255751 | 0.85 | ALOX15 (0.43) | PIK3R1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL27811909 | 0.81 | PIK3R1 (0.39) | PIK3R1PIK3CAADORA2ACSNK1A1CSNK1D | |
| SCHEMBL13930939 | 0.77 | NPC1 (0.52) | PIK3R1PIK3CAMAPTHPGDKDM4E | |
| SCHEMBL15364053 | 0.77 | PIK3R1 (0.42) | PIK3R1PIK3CAADORA2ACSNK1A1CSNK1D | |
| SCHEMBL3250263 | 0.75 | LMNA (0.37) | MAPTHPGDKDM4EALDH1A1PPARG | |
| SCHEMBL15364221 | 0.74 | ALOX15 (0.43) | PIK3R1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL3261757 | 0.74 | ALOX15 (0.54) | PIK3R1PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-10112930-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2017-12-28 | — | — | US | disclosed |
| EP-2786994-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-3233080-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | Monsanto Technology LLC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | disclosed |
| US-20150335020-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-11-26 | — | — | US | disclosed |
| EP-2947080-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Monsanto Technology LLC (US) | 2015-11-25 | — | — | EP | disclosed |
| US-9125410-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-06-04 | — | — | US | disclosed |
| EP-2786994-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786993-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786992-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-10112930-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | PIK3R1 1758/4885PIK3CA 1061/4885PIK3CD 491/4885 |
| US-20150335020-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | CYP51A1, MT-CO3, ACOX3 | PIK3R1 2056/4885PIK3CA 541/4885PIK3CD 179/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | PIK3R1 2402/4885PIK3CA 1684/4885PIK3CD 1066/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | PIK3R1 1956/4885PIK3CA 1361/4885PIK3CD 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.