Diethylhomospermine

Diethylhomospermine

SCHEMBL426504

CCNCCCCNCCCCNCCCCNCC

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.93
CYP1A2 P05177 3/20 0.93
MEN1 O00255 2/20 0.86
KMT2A Q03164 2/20 0.86
GLA P06280 1/20 0.86
TSHR P16473 3/20 0.69
KDM1A O60341 5/20 0.68
ALDH1A1 P00352 1/20 0.62
SAT1 P21673 3/20 0.57
TP53 P04637 1/20 0.50
CA12 O43570 2/20 0.44
F13A1 P00488 2/20 0.44
CA2 P00918 2/20 0.44
ALOX15 P16050 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
THPO P40225 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL429223 1.00 CYP2C19 (0.93) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL6899291 0.96 CYP2C19 (1.00) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL4157457 0.96 CYP2C19 (1.00) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL7513770 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA
Hydrochloric Acid SCHEMBL3877574 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL7097560 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL4167237 0.96 CYP2C19 (1.00) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL7091884 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL12085573 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA
SCHEMBL7096788 0.96 CYP2C19 (0.87) CYP2C19CYP1A2MEN1KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332118-A1 NOVEL ORAL CARE FORMULATIONS FOR TREATMENT OF XEROSTOMIA LIVIONEX INC (US) 2025-10-30 US claimed
EP-4504163-A1 NOVEL ORAL CARE FORMULATIONS FOR TREATMENT OF XEROSTOMIA Livionex, Inc. (US) 2025-02-12 EP claimed
CN-119384274-A Novel oral care formulations for the treatment of xerostomia 利维昂尼克斯公司 2025-01-28 CN claimed
US-12194010-B2 Methods and compositions to prevent and treat disorders associated with mutations in the ODC1 gene BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-01-14 US claimed
WO-2023196667-A1 NOVEL ORAL CARE FORMULATIONS FOR TREATMENT OF XEROSTOMIA LIVIONEX, Inc. (US) 2023-10-12 WO claimed
WO-2023147169-A2 NOVEL LIQUID FORMULATIONS FOR IRON CHELATION LIVIONEX, Inc. (US) 2023-08-03 WO claimed
EP-2941128-B1 ANTIMICROBIAL COMPOSITIONS BHUSHAN RAJIV (US) 2023-06-28 EP claimed
EP-1937235-A2 METHODS FOR TREATING VIRAL INFECTIONS USING POLYAMINE ANALOGS Pathologica, LLC. (US) 2008-07-02 EP claimed
US-20070078187-A1 METHODS FOR TREATING VIRAL INFECTIONS USING POLYAMINE ANALOGS PATHOLOGICA, LLC. (US) 2007-04-05 US claimed
WO-2007035957-A2 METHODS FOR TREATING VIRAL INFECTIONS USING POLYAMINE ANALOGS PATHOLOGICA, LLC. (US) 2007-03-29 WO claimed
US-7087648-B1 Methods for modulating macrophage proliferation using polyamine analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-08-08 US claimed
US-20050159493-A1 Methods for modulating macrophage proliferation using polyamine analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2005-07-21 US claimed
EP-1448183-A2 TREATMENT OF NEURODEGENERATIVE DISORDERS THROUGH THE MODULATION OF THE POLYAMINE PATHWAY ALS Therapy Development Foundation, Inc. (US) 2004-08-25 EP claimed
US-20030158262-A1 Treatment of neurodegenerative disorders through the modulation of the polyamine pathway ALS THERAPY DEVELOPMENT FOUNDATION, INC. 2003-08-21 US claimed
WO-2003043616-A2 TREATMENT OF NEURODEGENERATIVE DISORDERS THROUGH THE MODULATION OF THE POLYAMINE PATHWAY ALS THERAPY DEVELOPMENT FOUNDATION, INC. (US) 2003-05-30 WO claimed
EP-3946547-B1 DEVICES AND METHODS FOR DELIVERING PHARMACEUTICAL COMPOSITIONS PINOVA THERAPEUTICS INC (US) 2026-03-25 EP disclosed
EP-4687900-A2 COMBINATION TREATMENT FOR OVARIAN CANCER The Johns Hopkins University (US) 2026-02-11 EP disclosed
US-20020067472-A1 Linear polyamine compounds and polyamine anticancer agents IWATA MASAAKI (JP) 2002-06-06 US disclosed
US-6319956-B1 N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. RIKEN (JP) 2001-11-20 US disclosed
EP-1061130-A1 RNA POLYMERASE TRANSCRIPTION PROMOTERS AND METHOD FOR DETERMINING BASE SEQUENCE Riken (JP) 2000-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332118-A1 NOVEL ORAL CARE FORMULATIONS FOR TREATMENT OF XEROSTOMIA STOM, TAS2R40, SLC14A1 CYP2C19 2846/4885CYP1A2 4147/4885MEN1 3203/4885
US-20070078187-A1 METHODS FOR TREATING VIRAL INFECTIONS USING POLYAMINE ANALOGS GLS, SHMT2, ARG2 CYP2C19 3039/4885CYP1A2 3619/4885MEN1 446/4885
US-20030158262-A1 Treatment of neurodegenerative disorders through the modulation of the polyamine pathway ODC1, SRM, OTC CYP2C19 4855/4885CYP1A2 4604/4885MEN1 4302/4885
US-20050159493-A1 Methods for modulating macrophage proliferation using polyamine analogs ARG1, MKI67, CSF1R CYP2C19 4826/4885CYP1A2 4411/4885MEN1 865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.