SCHEMBL4266733

SCHEMBL4266733

OCC(O)COCCOCCOCCOCC(O)CO

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.58
LMNA P02545 4/20 0.44
ALDH1A1 P00352 1/20 0.44
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP1A2 P05177 2/20 0.38
AGTR1 P30556 1/20 0.38
THRB P10828 1/20 0.36
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808502 1.00 USP2 (0.58) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL1881943 0.97 USP2 (0.60) USP2LMNAALDH1A1MEN1KMT2A
Water SCHEMBL28291844 0.94 USP2 (0.58) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL5713071 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL12050435 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL867745 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL27620890 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL11352485 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL541678 0.92 MEN1 (0.55) USP2LMNAALDH1A1MEN1KMT2A
SCHEMBL27953890 0.90 USP2 (0.67) USP2LMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11231632-B2 Low-volatile electro-optic electrolyte solvents containing cylic organic carbonates GENTEX CORPORATION (US) 2022-01-25 US disclosed
US-20200192173-A1 LOW-VOLATILE ELECTRO-OPTIC ELECTROLYTE SOLVENTS CONTAINING CYLIC ORGANIC CARBONATES GENTEX CORPORATION (US) 2020-06-18 US disclosed
US-20090110649-A1 ANTIPRURITIC COSMETIC AND DERMATOLOGICAL PREPARATIONS BEIERSDORF AG (DE) 2009-04-30 US disclosed
US-20060093633-A1 Cosmetic and/or dermatological preparation comprising 2,3-dibenzylbutyrolactones BEIERSDORF AG (DE) 2006-05-04 US disclosed
US-20030147928-A1 Water, oil in water emulsifiers, optionally coemulsifiers, oil phase(s), polidocanol and an essential oil; saturated cloth; immediate and long-lasting effect BEIERSDORF AG 2003-08-07 US disclosed
US-20030091605-A1 Use of alpha-lipoic acid for producing cosmetic or dermatological preparations for regenerating stressed skin, in particular aged skin BEIERSDORF AG 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090110649-A1 ANTIPRURITIC COSMETIC AND DERMATOLOGICAL PREPARATIONS POLR1C, POLD3, SMURF1 USP2 942/4885LMNA 3022/4885ALDH1A1 4375/4885
US-20030091605-A1 Use of alpha-lipoic acid for producing cosmetic or dermatological preparations for regenerating stressed skin, in particular aged skin CUTA, LIPA, LPO USP2 2107/4885LMNA 793/4885ALDH1A1 257/4885
US-20060093633-A1 Cosmetic and/or dermatological preparation comprising 2,3-dibenzylbutyrolactones DPM1, TYR, DSG1 USP2 2534/4885LMNA 1421/4885ALDH1A1 548/4885
US-20030147928-A1 Water, oil in water emulsifiers, optionally coemulsifiers, oil phase(s), polidocanol and an essential oil; saturated cloth; immediate and long-lasting effect POLD1, POLD3, POLI USP2 553/4885LMNA 2339/4885ALDH1A1 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.