SCHEMBL4281484

SCHEMBL4281484

CC1=C(c2ccccc2)OS(=O)(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 4/20 0.39
CA12 O43570 3/20 0.37
PDGFRA P16234 1/20 0.34
MAPK8 P45983 1/20 0.34
CDK5 Q00535 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
KDM4E B2RXH2 6/20 0.32
GAA P10253 4/20 0.32
MAPT P10636 3/20 0.32
NOTUM Q6P988 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 3/20 0.32
CA2 P00918 2/20 0.32
USP2 O75604 1/20 0.32
CA1 P00915 1/20 0.32
BCHE P06276 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3189685 0.77 CA9 (0.38) CA9CA12PDGFRAMAPK8CDK5
SCHEMBL28739981 0.70 CA12 (0.43) CA9CA12KDM4EGAAMAPT
SCHEMBL3180645 0.70 CA9 (0.43) CA9
SCHEMBL3183012 0.66 CA9 (0.50) CA9CA12KDM4EGAAMAPT
SCHEMBL6361101 0.65 ALDH1A1 (0.40) CA9CA12KDM4EGAAMAPT
SCHEMBL1384629 0.64 KDM4E (0.47) CA9CA12KDM4ETDP1ALDH1A1
SCHEMBL9065124 0.63 KDM4E (0.46) CA9CA12KDM4ETDP1ALDH1A1
SCHEMBL9065126 0.63 KDM4E (0.46) CA9CA12KDM4ETDP1ALDH1A1
SCHEMBL9338651 0.61 PTGS2 (0.45) PDGFRAMAPK8CDK5CLK4KDM4E
SCHEMBL6308790 0.59 GPR3 (0.39) CA9CA12MAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
EP-2859961-A2 Methods and compositions for metal nanoparticle treated surfaces Avent, Inc. (US) 2015-04-15 EP disclosed
EP-1991365-B1 METHODS FOR FORMING SILVER-NANOPARTICLE TREATED SURFACES KIMBERLY CLARK CO (US) 2014-12-24 EP disclosed
US-20130122321-A1 Methods and Compositions for Metal Nanoparticle Treated Surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-05-16 US disclosed
US-20130122321-A1 Methods and Compositions for Metal Nanoparticle Treated Surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-05-16 US disclosed
US-20130122321-A1 Methods and Compositions for Metal Nanoparticle Treated Surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-05-16 US disclosed
US-8361553-B2 Methods and compositions for metal nanoparticle treated surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-01-29 US disclosed
US-8361553-B2 Methods and compositions for metal nanoparticle treated surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-01-29 US disclosed
US-8361553-B2 Methods and compositions for metal nanoparticle treated surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-01-29 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
US-7408059-B2 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide; cyclizing a beta-ketoamide-N-sulfonic acid with an acid anhydride DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-08-05 US disclosed
US-20070207335-A1 Methods and compositions for metal nanoparticle treated surfaces AVANOS MEDICAL SALES, LLC 2007-09-06 US disclosed
US-20070207335-A1 Methods and compositions for metal nanoparticle treated surfaces AVANOS MEDICAL SALES, LLC 2007-09-06 US disclosed
US-20070207335-A1 Methods and compositions for metal nanoparticle treated surfaces AVANOS MEDICAL SALES, LLC 2007-09-06 US disclosed
US-20050182255-A1 Method for producing 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or salt thereof DAICEL CHEMICAL INDUSTRIES, LTD. 2005-08-18 US disclosed
EP-1564211-A1 Method for producing 3,4-Dihydro-1,2,3-Oxathiazin-4-one-2,2-Dioxide compound or salt thereof Daicel Chemical Industries, Ltd. (JP) 2005-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050182255-A1 Method for producing 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or salt thereof CA2, HAO2, SRD5A2 CA9 124/4885CA12 37/4885PDGFRA 2026/4885
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 CA9 1224/4885CA12 923/4885PDGFRA 2389/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 CA9 1224/4885CA12 923/4885PDGFRA 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.