Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285371 | 0.74 | CYP2B6 (0.41) | HPGDCYP2B6EPHX2GAASMN1; SMN2 | |
| SCHEMBL4285382 | 0.71 | GAA (0.50) | HPGDEPHX2GAASMN1; SMN2NPC1 | |
| Acetic Acid SCHEMBL29103732 | 0.67 | EPHX2 (0.50) | EPHX2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL23903305 | 0.67 | ALDH1A1 (0.50) | HPGDEPHX2GAASMN1; SMN2NPC1 | |
| SCHEMBL30608899 | 0.65 | CYP2B6 (0.43) | CYP2B6MAPTCHRM3NPSR1MEN1 | |
| SCHEMBL28515156 | 0.64 | EPHX2 (0.47) | EPHX2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9680992 | 0.64 | ALDH1A1 (0.51) | CYP2B6GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11513547 | 0.63 | L3MBTL1 (0.42) | NPC1RAB9AMAPTLMNAMEN1 | |
| SCHEMBL13072375 | 0.63 | PPARA (0.50) | MAPTKDM4EMEN1KMT2ATSHR | |
| SCHEMBL26059882 | 0.63 | PDK1 (0.43) | MAPTKDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069300-A2 | MULTIMEDIATOR TRANSPORTER INHIBITORS FOR USE IN TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PREXA PHARMACEUTICALS, INC. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008024371-A2 | MULTIMEDIATOR TRANSPORTER INHIBITORS FOR USE IN TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PREXA PHARMACEUTICALS, INC. (US) | 2008-02-28 | — | — | WO | disclosed |