Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.63 |
| ▸ | F7 | P08709 | 5/20 | 0.63 |
| ▸ | F3 | P13726 | 5/20 | 0.63 |
| ▸ | PPARG | P37231 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.63 |
| ▸ | PPARD | Q03181 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718642 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6926291 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6926109 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6926111 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL4287214 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6926294 | 1.00 | PTGS1 (0.64) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL20830249 | 0.98 | PTGS1 (0.66) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL7716329 | 0.93 | PTGS1 (0.68) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6927971 | 0.93 | PTGS1 (0.68) | PTGS1ALDH1A1CYP19A1F7F3 | |
| SCHEMBL6927968 | 0.93 | PTGS1 (0.68) | PTGS1ALDH1A1CYP19A1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149496-A1 | TREATMENT OF DIABETES AND COMPLICATIONS THEREOF AND RELATED DISORDERS | CENTRAL NORTHERN ADELAIDE HEALTH SERVICE (AU) | 2009-12-17 | — | — | WO | disclosed |
| US-20090215895-A1 | Therapeutic and carrier molecules | PEPLIN BIOLIPIDS PTY LTD (AU) | 2009-08-27 | — | — | US | disclosed |
| US-20090215895-A1 | Therapeutic and carrier molecules | PEPLIN BIOLIPIDS PTY LTD (AU) | 2009-08-27 | — | — | US | disclosed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-6376688-B1 | Modified polyunsaturated fatty acids | PEPTIDE TECHNOLOGY LIMITED (AU) | 2002-04-23 | — | — | US | disclosed |
| EP-0869941-B1 | MODIFIED POLYUNSATURATED FATTY ACIDS | PEPTECH LTD (AU) | 2001-12-12 | — | — | EP | disclosed |
| EP-0869941-A1 | MODIFIED POLYUNSATURATED FATTY ACIDS | PEPTIDE TECHNOLOGY LTD (AU) | 1998-10-14 | — | — | EP | disclosed |
| EP-0869941-A4 | — | — | 1998-10-14 | — | — | EP | disclosed |
| WO-1996011908-A1 | MODIFIED POLYUNSATURATED FATTY ACIDS | PEPTIDE TECHNOLOGY LIMITED (AU) | 1996-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215895-A1 | Therapeutic and carrier molecules | PHKG1, PHKG2, DGKB | PTGS1 107/4885ALDH1A1 3631/4885CYP19A1 1843/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | PTGS1 5/4885ALDH1A1 884/4885CYP19A1 325/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | PTGS1 12/4885ALDH1A1 316/4885CYP19A1 457/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | PTGS1 5/4885ALDH1A1 884/4885CYP19A1 325/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | PTGS1 5/4885ALDH1A1 884/4885CYP19A1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.