Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CPS1 | P31327 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751893 | 0.90 | MGLL (0.42) | NPSR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4749712 | 0.86 | RAB9A (0.46) | NPSR1MAPTHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4288154 | 0.86 | CPS1 (0.52) | L3MBTL1CPS1ABHD6MGLLALDH1A1 | |
| SCHEMBL4750109 | 0.83 | ALDH1A1 (0.40) | NPSR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4753498 | 0.82 | ALDH1A1 (0.48) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4753413 | 0.82 | TDP1 (0.51) | LMNASMN1; SMN2L3MBTL1GAATSHR | |
| SCHEMBL4296960 | 0.80 | L3MBTL1 (0.47) | LMNAMAPTSMN1; SMN2L3MBTL1MGLL | |
| SCHEMBL4297012 | 0.79 | MEN1 (0.46) | NPSR1LMNAMAPTALOX12HTT | |
| SCHEMBL4301342 | 0.76 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ABHD6MGLLALDH1A1 | |
| SCHEMBL4298277 | 0.76 | KDM4E (0.45) | LMNAMAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | NPSR1 2099/4885LMNA 1785/4885MAPT 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.