Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750109 | 0.86 | ALDH1A1 (0.40) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4751878 | 0.84 | CYP1A2 (0.49) | MEN1KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL4288263 | 0.82 | NPSR1 (0.43) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL4751893 | 0.82 | MGLL (0.42) | MEN1KMT2ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4753498 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL4750352 | 0.78 | RAB9A (0.55) | MEN1KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL4752657 | 0.77 | SMN1; SMN2 (0.50) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL4293429 | 0.77 | FKBP1A (0.48) | TDP1MEN1KMT2ARAB9AFKBP1A | |
| SCHEMBL4299441 | 0.77 | MGLL (0.47) | SMN1; SMN2GAA | |
| SCHEMBL4297012 | 0.76 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |